Biochemistry and Molecular Biology

  • Kuwait

Research Output

Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes

Qaddoumi, M. G., Alanbaei, M., Hammad, M. M., Al Khairi, I., Cherian, P., Channanath, A., Thanaraj, T. A., Al-Mulla, F., Abu-Farha, M. & Abubaker, J., 10 Apr 2020, In : Scientific Reports. 10, 1, p. 6170 6170.

Research output: Contribution to journalArticle

312-LB: Irisin, Meteorin-Like Protein, and Bone Remodeling Markers in T2D and Obesity

ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., JAMAL, MOHAMMAD., AL-SABAH, SULEIMAN., Ali, H., DSOUZA, CAROL., ALOTAIBI, FATEMAH. KULAIB., AL-ALI, WALEED. & AL-KHALEDI, GHANIM. MOHAMMAD., 2019, American Diabetes Association Inc.

Research output: Other contribution

A420 The Effect of Sleeve Gastrectomy on The Uncoupling Proteins in Animal Rat Model

Jamal, M., Abu-Farha, M., Al-Khaledi, G., Al-Sabah, S., Ali, H., Al-Otaibi, F., Dsouza, C., Al-Ali, W. & Al-Mulla, F., 2019, In : Surgery for Obesity and Related Diseases. 15, 10, p. S171

Research output: Contribution to journalArticle

Angiopoietin-like proteins in multiple sclerosis

Al-Temaimi, R., Cherian, P., Abu-Farha, M. & Alroughani, R., 15 May 2019, In : Journal of Neuroimmunology. 330, p. 31-34 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

ANGPTL4 a predictive marker for diabetic nephropathy.

Alshawaf, E., Abu-Farha, M., Sriraman, D., ALSAIRAFI, ZAHRA., Al Khairi, I., Cherian, P., Mohamed Ali Yaseen, H., Mathur, A., Al-Mulla, F., AlAttar, A. & Abubaker, J., 1 Jan 2019, In : Journal of Diabetes Research. 2019, p. 4943191 4943191.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
4 Citations (Scopus)

Corrigendum: Caveolin-1 Variant Is Associated With the Metabolic Syndrome in Kuwaiti Children: Caveolin-1 variant is associated with the metabolic syndrome in Kuwaiti children (Frontiers in Genetics ( 2018) 9 (689) DOI: 10.3389/fgene.2018.00689)

Nizam, R., Al-Ozairi, E., Goodson, J. M., Melhem, M., Davidsson, L., Alkhandari, H., Al Madhoun, A., Shamsah, S., Qaddoumi, M., Alghanim, G., Alhasawi, N., Abu-Farha, M., Abubaker, J., Shi, P., Hartman, M-L., Tavares, M., Bitar, M., Ali, H., Arefanian, H., Devarajan, S. & 4 others, Al-Refaei, F., Alsmadi, O., Tuomilehto, J. & Al-Mulla, F., 1 Jan 2019, In : Frontiers in Genetics. 10, MAR, p. 221 1 p., 221.

Research output: Contribution to journalComment/debate

Dasman Diabetes Biobank Kuwait – Operations Overview

Sriraman, D., Lopez, V., Mathur, A., Chandy, B. S., Shyamsundar, A., Jose, R. M., Vijayan, V., Abu-Farha, M. & Al-Mulla, F., 2019.

Research output: Contribution to conferencePoster

Dynamic oligomerization of hRAGE's transmembrane and cytoplasmic domains within SDS micelles

Zamoon, J., Madhu, D. & Ahmed, I., 1 Jun 2019, In : International Journal of Biological Macromolecules. 130, p. 10-18 9 p.

Research output: Contribution to journalArticle

Higher Levels of ANGPTL5 in the Circulation of Subjects With Obesity and Type 2 Diabetes Are Associated With Insulin Resistance

Alghanim, G., Qaddoumi, M. G., Alhasawi, N., Cherian, P., Al-Khairi, I., Nizam, R., Alkayal, F., Alanbaei, M., Tuomilehto, J., Abubaker, J., Abu-Farha, M. & Al-Mulla, F., 1 Jan 2019, In : Frontiers in Endocrinology. 10, p. 495 1 p., 495.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Irisin, Meteorin-like protein and Bone remodeling markers in Obesity and T2D

Cherian, P., Al Khairi, I., Abubaker, J., Abu-Farha, M., Mohamed, G., Mohamed Ali Yaseen, H., DSOUZA, CAROL., Al-Otaibi, F., Al-Ali, W., AL-KHALEDI, GHANIM. MOHAMMAD. & Al-Mulla, F., 9 Jun 2019.

Research output: Contribution to conferencePoster

4 Citations (Scopus)

PKD1 Duplicated regions limit clinical Utility of Whole Exome Sequencing for Genetic Diagnosis of Autosomal Dominant Polycystic Kidney Disease

Mohamed Ali Yaseen, H., Al-Mulla, F., Hussain, N., Naim, M., Asbeutah, A. M., AlSahow, A., Abu-Farha, M., Abubaker, J., Al Madhoun, A., Ahmad, S. & Harris, P. C., 11 Mar 2019, In : Scientific Reports. 9, 1, p. 4141 4141.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Reduced miR-181d level in obesity and its role in lipid metabolism via regulation of ANGPTL3.

Abu-Farha, M., Cherian, P., Al Khairi, I., Nizam, R., Alkandari, A., Arefanian, H., Tuomilehto, J., Al-Mulla, F. & Abubaker, J., 14 Aug 2019, In : Scientific Reports. 9, 1, p. 11866 11866.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Associations of adiposity and parental diabetes with prediabetes among adolescents in Kuwait: A cross-sectional study

Almari, M., Alsaedi, S., Mohammad, A. & H M Ziyab, A., 1 Dec 2018, In : Pediatric Diabetes. 19, 8, p. 1362-1369 8 p.

Research output: Contribution to journalArticle

Biphasic changes in angiopoietin-like 8 level after laparoscopic sleeve gastrectomy and type 2 diabetes remission during a 1-year follow-up

Alshawaf, E., Al Ozairi, E., Al-Asfar, F., Al-Beloushi, S., Kumari, S., Tuomilehto, J. & Arefanian, H., 1 Sep 2018, In : Surgery for Obesity and Related Diseases. 14, 9, p. 1284-1294 11 p.

Research output: Contribution to journalArticle

Open Access

Connaissance, attitudes, comportements et pratiques associés au diabète sucré au koweït

Translated title of the contribution: Knowledge, attitudes, behaviours and practices towards diabetes mellitus in kuwaitCarballo, M., Mohammad, A., Maclean, E. C., Khatoon, N., Waheedi, M. & Abraham, S., 1 Nov 2018, In : Eastern Mediterranean Health Journal. 24, 11, p. 1098-1102 5 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

CVD Risk Pre- and Post-metabolic surgery from an Atherogenic Index of Plasma perspective

Alshawaf, E., Al Ozairi, E., Al-Asfar, F. & Arefanian, H., 14 Nov 2018.

Research output: Contribution to conferencePoster

DUSP1 Is a Potential Marker of Chronic Inflammation in Arabs with Cardiovascular Diseases

Khadir, A., Kavalakatt, S., Dehbi, M., Alarouj, M., Bennakhi, A., Tiss, A. & Elkum, N., 1 Jan 2018, In : Disease Markers. 2018, 9529621.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Elevated ANGPTL5 Level in the Circulation of Obese and Type 2 Diabetic People

Abu-Farha, M., Alhasawi, N., Qaddoumi, M., Al-Mulla, F., Tuomilehto, J., Alanbaei, M. & Abubaker, J., 2018, American Diabetes Association Inc.

Research output: Other contribution

Fetuin-A levels are increased in the adipose tissue of diabetic obese humans but not in circulation

Khadir, A., Kavalakatt, S., Madhu, D., Hammad, M., Sriraman, D., Tuomilehto, J. & Tiss, A., 22 Dec 2018, In : Lipids in Health and Disease. 17, 1, 291.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
Open Access
4 Citations (Scopus)

Hypomagnesaemia in Diabetes Patients: Comparison of Serum and Intracellular Measurement of Responses to Magnesium Supplementation and its Role in Inflammation

Alam-Eldin, N., Zghoul, N., Weglicki, W., Mak, I. & Silver, B., 2 Aug 2018.

Research output: Contribution to conferencePoster

Open Access
4 Citations (Scopus)

Increased circulation and adipose tissue levels of DNAJC27/RBJ in obesity and type 2-diabetes

Cherian, P., Al khairi, I., Sriraman, D., Al-Enezi, A., Al-Sultan, D., AlOtaibi, M., Al-Enezi, S., Tuomilehto, J., Al-Mulla, F., Abubaker, J. & Abu-Farha, M., 7 Aug 2018, In : Frontiers in Endocrinology. 9, AUG, 423.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Increased expression of Meteorin-like hormone in Type 2 diabetes and obesity and its association with irisin

Al Khairi, I., 5 Oct 2018, 5th middle east molecular biology congress and exhibition .

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Increased level of angiopoietin like proteins 4 and 8 in people with sleep apnea

Al-Terki, A., Abu-Farha, M., Al Khairi, I., Cherian, P., Sriraman, D., Shyamsundar, A., Ali, S., Tuomilehto, J. & Abubaker, J., 2018, In : Frontiers in Endocrinology. 9

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

MAGI proteins can differentially regulate the signaling pathways of 5-HT2AR by enhancing receptor trafficking and PLC recruitment

Hammad, M., Dunn, H. A. & Ferguson, S. S. G., 1 Jul 2018, In : Cellular Signalling. 47, p. 109-121 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Neurophysiological effects of aging: A P200 ERP study

KH H Bourisly, A. & Shuaib, A., 1 Jan 2018, In : Translational Neuroscience. 9, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Optimization of low-level light therapy's illumination parameters for spinal cord injury in a rat model

Shuaib, A. & KH H Bourisly, A., 1 Jan 2018, Mechanisms of Photobiomodulation Therapy XIII. Carroll, J. D., Arany, P. & Hamblin, M. R. (eds.). 1047703. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10477).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photobiomodulation optimization for spinal cord injury rat phantom model

Shuaib, A. & KH H Bourisly, A., 1 Jan 2018, In : Translational Neuroscience. 9, 1, p. 67-71 5 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
Open Access
11 Citations (Scopus)

Sex differences in electrophysiology: P200 event-related potential evidence

KH H Bourisly, A. & Shuaib, A., 1 Jan 2018, In : Translational Neuroscience. 9, 1, p. 72-77 6 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Structural MRI in neurodegenerative non-alzheimer’s dementia

Di Paola, M. & KH H Bourisly, A., 1 Jan 2018, Neuromethods. p. 241-265 25 p. (Neuromethods; vol. 136).

Research output: Chapter in Book/Report/Conference proceedingChapter

The synergy between palmitate and TNF-a for ccl2 production is dependent on the trif/irf3 pathway: implications for metabolic inflammation

Ahmad, R., Abu-AlRoub, A., Kchumon, S., Akther, N., Thomas, R., Kumari, M., Koshy, M., Tiss, A., Hannun, Y. A., Tuomilehto, J., Sindhu, S. & Rosen, E. D., 15 May 2018, In : Journal of Immunology. 200, 10, p. 3599-3611 13 p.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)
2017

ANGPTL8 (betatrophin) role in diabetes and metabolic diseases

Abu-Farha, M., Abubaker, J. & Tuomilehto, J., 1 Nov 2017, In : Diabetes/Metabolism Research and Reviews. 33, 8, e2919.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Application of High-Dimensional Statistics and Network Based Visualization Techniques on Arab Diabetes and Obesity Data

Mall, R., Rawi, R., Ullah, E., Kunji, K., Khadir, A., Tiss, A., Abubaker, J., Kulinski, M. A., Ramzi, M. M. & Bensmail, H., 2017, In : Journal of Health & Medical Informatics. 8, 2, p. 2

Research output: Contribution to journalArticle

Open Access

Deciphering the role of ANGPTL8 and its Variants in Insulin Resistance and Lipid Metabolism by Proteomics

Abu-farha, M., Cherian, P., Al-khairi, I. & Abubaker, J., 2017, PROTEIN SCIENCE. Vol. 26. p. 175-175 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution