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2020

A comprehensive germline variant and expression analyses of ACE2, TMPRSS2 and SARS-CoV-2 activator FURIN genes from the Middle East: Combating SARS-CoV-2 with precision medicine.

Al-Mulla, F., Mohammad, A., Al Madhoun, A., Haddad, D., Ali, H., Eaaswarkhanth, M., John, S. E., Nizam, R., Channanath, A., Abu-Farha, M., Ahmad, R., Abubaker, J. & Thanaraj, A. T., 16 May 2020, In : BioRxiv. BIORXIV/2020/099176, p. 1 to 28 28 p.

Research output: Contribution to journal › Article

Adaptive fitness advantage in ancestors: a major health risk to a present-day Arab population

Eaaswarkhanth, M., Campelo dos Santos, A. L., Gokcumen, O., Al-Mulla, F. & Thanaraj, A. T., 20 Apr 2020.

Research output: Contribution to conference › Poster

Open Access

Adipose tissue gene expression of CXCL10 and CXCL11 modulates inflammatory markers in obesity: implications for metabolic inflammation and insulin resistance

Kochumon, S., Madhoun, A. A., Al-Rashed, F., Azim, R., Al-Ozairi, E., Al-Mulla, F. & Ahmad, R., 2020, In : Therapeutic Advances in Endocrinology and Metabolism. 11, p. 2042018820930902

Research output: Contribution to journal › Article

Open Access

Adopting identification standards in the medical device supply chain

Abdulsalam, Y., Alhuwail, D. & Schneller, E. S., 1 Jan 2020, In : International Journal of Information Systems and Supply Chain Management. 13, 1, p. 1-14 14 p.

Research output: Contribution to journal › Article

Correlation of circulating ANGPTL5 levels with obesity, high sensitivity C-reactive protein and oxidized low-density lipoprotein in adolescents

Hammad, M. M., Abu-Farha, M., Al-Taiar, A., Alam-Eldin, N., Al-Sabah, R., Shaban, L., Al-Mulla, F., Abubaker, J. & Rahman, A., 14 Apr 2020, In : Scientific Reports. 10, 1, p. 6330 6330.

Research output: Contribution to journal › Article

Could the D614G substitution in the SARS-CoV-2 spike (S) protein be associated with higher COVID-19 mortality?

Eaaswarkhanth, M., Al Madhoun, A. & Al-Mulla, F., Jul 2020, In : International Journal of Infectious Diseases. 96, p. 459-460 2 p.

Research output: Contribution to journal › Article

Open Access
11 Citations (Scopus)

Effect of sleeve gastrectomy on the expression of meteorin-like (METRNL) and Irisin (FNDC5) in muscle and brown adipose tissue and its impact on uncoupling proteins in diet-induced obesity rats

Jamal, M. H., Abu-Farha, M., Al-Khaledi, G., Al-Sabah, S., Ali, H., Cherian, P., Al-Khairi, I., AlOtaibi, F., Al-Ali, W., Bosso, M., Dsouza, C., Abubaker, J. & Al-Mulla, F., 31 Jul 2020, In : Surgery for Obesity and Related Diseases.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients

Sindhu, S., Kochumon, S., Thomas, R., Bennakhi, A., Al-Mulla, F. & Ahmad, R., 16 Mar 2020, In : cells. 9, 3

Research output: Contribution to journal › Article

Evaluating the accessibility of higher education institution websites in the State of Kuwait: empirical evidence

AlMeraj, Z., Boujarwah, F., Alhuwail, D. & Qadri, R., 2020, (Accepted/In press) In : Universal Access in the Information Society.

Research output: Contribution to journal › Article

Fetuin-a expression profile in mouse and human adipose tissue

Khadir, A., Kavalakatt, S., Madhu, D. & Tiss, A., 12 Mar 2020, In : Lipids in Health and Disease. 19, 1, 38.

Research output: Contribution to journal › Review article

Open Access

FTO Variant rs1421085 Associates With Increased Body Weight, Soft Lean Mass, and Total Body Water Through Interaction With Ghrelin and Apolipoproteins in Arab Population

Hebbar, P., Abu-Farha, M., Mohammad, A., Alkayal, F., Melhem, M., Abubaker, J., Al-Mulla, F. & Thanaraj, T. A., 31 Jan 2020, In : Frontiers in Genetics. 10, p. 1411 1411.

Research output: Contribution to journal › Article

Open Access
1 Citation (Scopus)

Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population

Hebbar, P., Abu-Farha, M., Alkayal, F., Nizam, R., Elkum, N., Melhem, M., John, S. E., Channanath, A., Abubaker, J., Bennakhi, A., Al-Ozairi, E., Tuomilehto, J., Pitkaniemi, J., Alsmadi, O., Al-Mulla, F. & Thanaraj, T. A., 13 Jan 2020, In : Scientific Reports. 10, 1, p. 152 152.

Research output: Contribution to journal › Article

Open Access
1 Citation (Scopus)

Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population

Hebbar, P., Abubaker, J. A., Abu-Farha, M., Alsmadi, O., Elkum, N., Alkayal, F., John, S. E., Channanath, A., Iqbal, R., Pitkaniemi, J., Tuomilehto, J., Sladek, R., Al-Mulla, F. & Thanaraj, T. A., 9 Sep 2020, In : Human Genetics.

Research output: Contribution to journal › Article

Genome-wide Selection Scan in an Arabian Peninsula Population Identifies a TNKS haplotype Linked to Metabolic Traits and Hypertension.

Eaaswarkhanth, M., Campelo dos Santos, A. L., Gokcumen, O., Al-Mulla, F. & Thanaraj, A. T., 17 Mar 2020, In : Genome Biology and Evolution. 12, 3, p. 77-87 11 p.

Research output: Contribution to journal › Article

Open Access
1 Citation (Scopus)
1 Downloads (Pure)

Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication

Abdullah, A., Alkandari, A., Longenecker, J. C., Devarajan, S., Alkhatib, A., Al-Wotayan, R., Al-Duwairi, Q. & Tuomilehto, J., 1 Jan 2020, (Accepted/In press) In : Primary Care Diabetes.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Higher BDNF Levels in the Circulation is Associated with Angiogenesis, Inflammatory and Metabolic Biomarkers in Children

Hasan, A., Kochumon, S., Ali, S. & Mandani, F., 2020, (Accepted/In press).

Research output: Contribution to conference › Poster

Identification of HLA‐C*16:46 allele in a Kuwaiti individual

Jacob, S., 1 Jan 2020, In : HLA. 95, 1, p. 71-72 2 p.

Research output: Contribution to journal › Article

Increasing the Duration of Light Physical Activity Ameliorates Insulin Resistance Syndrome in Metabolically Healthy Obese Adults

Al-Rashed, F., Alghaith, A., Azim, R., AlMekhled, D., Thomas, R., Sindhu, S. & Ahmad, R., 11 May 2020, In : cells. 9, 5

Research output: Contribution to journal › Article

Open Access

Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes

Qaddoumi, M. G., Alanbaei, M., Hammad, M. M., Al Khairi, I., Cherian, P., Channanath, A., Thanaraj, T. A., Al-Mulla, F., Abu-Farha, M. & Abubaker, J., 10 Apr 2020, In : Scientific Reports. 10, 1, p. 6170 6170.

Research output: Contribution to journal › Article

Late bedtime and dental caries incidence in Kuwaiti children: A longitudinal multilevel analysis

Alqaderi, H., Tavares, M., Al-Mulla, F., Al-Ozairi, E. & Goodson, J. M., 2020, (Accepted/In press) In : Community Dentistry and Oral Epidemiology.

Research output: Contribution to journal › Article

Maturity-onset diabetes of the young (MODY): a time to act. a time to act

Mohammad Abdullah Al-kandari, H., Mahmoud Yousef Alabdulrazzaq, D., Davidsson, L. & Al-Mulla, F., Jul 2020, In : The Lancet Diabetes and Endocrinology. 8, 7, p. 565-566 2 p.

Research output: Contribution to journal › Letter

Open Access

MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort

Hammad, M. M., Abu-Farha, M., Hebbar, P., Cherian, P., Al Khairi, I., Melhem, M., Alkayal, F., Alsmadi, O., Thanaraj, T. A., Al-Mulla, F. & Abubaker, J., Jul 2020, In : Frontiers in Endocrinology. 11, p. 437 1 p.

Research output: Contribution to journal › Article

Method For Preventing Progression To Metabolic Syndrome

Al-Mulla, F., Nizam, R. & Al Madhoun, A., 4 Aug 2020, IPC No. US, Patent No. 10,731,219, B1, 19 Sep 2019

Research output: Patent

Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α

Al-Rashed, F., Ahmad, Z., Thomas, R., Melhem, M., Snider, A., Obeid, L., Al-Mulla, F., Hannun, Y. & Ahmad, R., 2020, In : BioRxiv.

Research output: Contribution to journal › Article

Plasma Calprotectin Is Associated with Obesity and Systemic Inflammation in Children

Hasan, A., Kochumon, S. & Mohammad Abdullah Al-kandari, H., Jun 2020.

Research output: Contribution to conference › Poster

Positively selected TNKS haplotype: from evolutionary advantage to the health risk in an Arabian Peninsula population

Eaaswarkhanth, M., Campelo dos Santos, A. L., Gokcumen, O., Al-Mulla, F. & Thanaraj, A. T., 6 Jun 2020.

Research output: Contribution to conference › Poster

PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases

Khadir, A., Madhu, D., Kavalakatt, S., Cherian, P., Alarouj, M., Bennakhi, A., Abubaker, J., Tiss, A. & Elkum, N., 2020, In : PloS one. 15, 1, e0227606.

Research output: Contribution to journal › Article

Open Access

Protocol for a randomised controlled trial to investigate the effect of home- And gym-based resistance exercise training on glycaemic control, body composition and muscle strength

Al Ozairi, E., Alsaeed, D., Alsaeed, D., Taliping, D., Jalali, M., Jalali, M., El Samad, A., Mashankar, A., Taghadom, E., Taghadom, E., Guess, N., Gill, J. M. R., Sattar, N., Gray, C., Welsh, P. & Gray, S. R., 22 Jun 2020, In : Trials. 21, 1, 557.

Research output: Contribution to journal › Article

Open Access

Repositioning of the global epicentre of non-optimal cholesterol

Imperial College London, 4 Jun 2020, In : Nature. 582, 7810, p. 73-77 5 p.

Research output: Contribution to journal › Article

Open Access
3 Citations (Scopus)

Role of Caveolin-1 in Diabetes and Its Complications

Haddad, D., Al Madhoun, A., Nizam, R. & Al-Mulla, F., 28 Jan 2020, In : Oxidative Medicine and Cellular Longevity. 2020, p. 9761539 9761539 .

Research output: Contribution to journal › Review article

Open Access
1 Citation (Scopus)

Soluble epoxide hydrolase 2 expression is elevated in obese humans and decreased by physical activity

Khadir, A., Kavalakatt, S., Madhu, D., Cherian, P., Al-Mulla, F., Abubaker, J. & Tiss, A., 2 Mar 2020, In : International Journal of Molecular Sciences. 21, 6, 2056.

Research output: Contribution to journal › Article

Open Access

Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes

Khadir, A., Kavalakatt, S., Madhu, D., Devarajan, S., Abubaker, J., Al-Mulla, F. & Tiss, A., 1 Dec 2020, In : Scientific Reports. 10, 1, 10635.

Research output: Contribution to journal › Article

Open Access

The GLP-1 analog exendin-4 modulates HSP72 expression and ERK1/2 activity in BTC6 mouse pancreatic cells

Madhu, D., Khadir, A., Hammad, M., Kavalakatt, S., Dehbi, M., Al-Mulla, F., Abubaker, J. & Tiss, A., Jul 2020, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1868, 7, p. 140426 140426.

Research output: Contribution to journal › Article

The role of lipid metabolism in COVID-19 virus infection and as a drug target

Abu-Farha, M., Thanaraj, T. A., Qaddoumi, M. G., Hashem, A., Abubaker, J. & Al-Mulla, F., 2 May 2020, In : International Journal of Molecular Sciences. 21, 10, 3544.

Research output: Contribution to journal › Review article

Open Access
5 Citations (Scopus)

The role of Raf kinase inhibitory protein in inflammation

Shenouda, S., Ahmad, R., Bosso, M. & Al-Mulla, F., 2020, Prognostic and therapeutic applications of RKIP in cancer. p. 299-316 17 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

The state of mental digi-therapeutics: A systematic assessment of depression and anxiety apps available for Arabic speakers

Alhuwail, D., Albaj, R., Ahmad, F. & Aldakheel, K., Mar 2020, In : International Journal of Medical Informatics. 135, 104056.

Research output: Contribution to journal › Article

1 Citation (Scopus)

The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19

Bosso, M., Thanaraj, T. A., Abu-Farha, M., Alanbaei, M., Abubaker, J. & Al-Mulla, F., 11 Sep 2020, In : Molecular Therapy - Methods and Clinical Development. 18, p. 321-327 7 p.

Research output: Contribution to journal › Review article

Open Access
2 Citations (Scopus)

Top concerns of tweeters during the COVID-19 pandemic: A surveillance study

Abd-Alrazaq, A., Alhuwail, D., Househ, M., Hai, M. & Shah, Z., Apr 2020, In : Journal of Medical Internet Research. 22, 4, e19016.

Research output: Contribution to journal › Article

Open Access
29 Citations (Scopus)
2019

1871-P: Mir 103/107 Regulates Lipid Metabolism by Inhibiting Betatrophin/ANGPTL8

ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., AL-MULLA, FAHD. & ABUBAKER, JEHAD., 2019, American Diabetes Association Inc.

Research output: Other contribution

268-LB: Investigating the Role of MPO and ANGPTL6 in Obesity and Diabetes and Their Potential Role in Wound Healing

QADDOUMI, MOHAMMAD. G., ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., CHANNANATH, ARSHAD. MOHAMED., ALANBAEI, MUATH., ABUBAKER, JEHAD. & AL-MULLA, FAHD., 2019, American Diabetes Association Inc.

Research output: Other contribution

312-LB: Irisin, Meteorin-Like Protein, and Bone Remodeling Markers in T2D and Obesity

ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., JAMAL, MOHAMMAD., AL-SABAH, SULEIMAN., Ali, H., DSOUZA, CAROL., ALOTAIBI, FATEMAH. KULAIB., AL-ALI, WALEED. & AL-KHALEDI, GHANIM. MOHAMMAD., 2019, American Diabetes Association Inc.

Research output: Other contribution

A420 The Effect of Sleeve Gastrectomy on The Uncoupling Proteins in Animal Rat Model

Jamal, M., Abu-Farha, M., Al-Khaledi, G., Al-Sabah, S., Ali, H., Al-Otaibi, F., Dsouza, C., Al-Ali, W. & Al-Mulla, F., 2019, In : Surgery for Obesity and Related Diseases. 15, 10, p. S171

Research output: Contribution to journal › Article

Acsl1 regulates tnfα-induced gm-csf production by breast cancer mda-mb-231 cells

Ahmad, R., Thomas, R., Al-Rashed, F., Akhter, N. & Al-Mulla, F., Oct 2019, In : Biomolecules. 9, 10, 555.

Research output: Contribution to journal › Article

Open Access
2 Citations (Scopus)

Acute effects of air pollution on mortality: A 17-year analysis in Kuwait

Achilleos, S., Al Ozairi, E., Alahmad, B., Garshick, E., Neophytou, A. M., Bouhamra, W., Yassin, M. F. & Koutrakis, P., 1 May 2019, In : Environment International. 126, p. 476-483 8 p.

Research output: Contribution to journal › Article

Open Access
15 Citations (Scopus)

Adipose tissue expression of CCL19 chemokine is positively associated with insulin resistance

Kchumon, S., Salem Alrashed, F., Abu-Farha, M., Sriraman, D., Tuomilehto, J. & Ahmad, R., 1 Feb 2019, In : Diabetes/Metabolism Research and Reviews. 35, 2, p. e3087 e3087.

Research output: Contribution to journal › Article

Open Access
5 Citations (Scopus)

Angiopoietin-like proteins in multiple sclerosis

Al-Temaimi, R., Cherian, P., Abu-Farha, M. & Alroughani, R., 15 May 2019, In : Journal of Neuroimmunology. 330, p. 31-34 4 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

ANGPTL4 a predictive marker for diabetic nephropathy.

Alshawaf, E., Abu-Farha, M., Sriraman, D., ALSAIRAFI, ZAHRA., Al Khairi, I., Cherian, P., Mohamed Ali Yaseen, H., Mathur, A., Al-Mulla, F., AlAttar, A. & Abubaker, J., 1 Jan 2019, In : Journal of Diabetes Research. 2019, p. 4943191 4943191.

Research output: Contribution to journal › Article

Open Access
3 Citations (Scopus)

A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations

Hebbar, P., Abubaker, J. A., Abu-Farha, M., Tuomilehto, J., Al-Mulla, F. & Thanaraj, A. T., 1 Jan 2019, In : Frontiers in Endocrinology. 10, JAN, p. 8 1 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

Assessing electronic health literacy in the state of Kuwait: Survey of internet users from an Arab state

Alhuwail, D. & Abdulsalam, Y., May 2019, In : Journal of Medical Internet Research. 21, 5, e11174.

Research output: Contribution to journal › Article

Open Access
3 Citations (Scopus)

Association between Adipose Tissue Interleukin-33 and Immunometabolic Markers in Individuals with Varying Degrees of Glycemia

Hasan, A., Kochumon, S., Al Ozairi, E., Tuomilehto, J. & Ahmad, R., Apr 2019, In : Disease Markers. 2019, 7901062, p. 7901062 7901062.

Research output: Contribution to journal › Article

Open Access
2 Citations (Scopus)