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2021
ACE2 and FURIN variants are potential predictors of SARS-CoV-2 outcome: A time to implement precision medicine against COVID-19
Al-Mulla, F., Mohammad, A., Al Madhoun, A., Haddad, D., Ali, H., Eaaswarkhanth, M., John, S. E., Nizam, R., Channanath, A., Abu-Farha, M., Ahmad, R., Abubaker, J. & Thanaraj, T. A., Feb 2021, In: Heliyon. 7, 2, e06133.Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial haplogroup J associated with higher risk of obesity in the Qatari population
Dashti, M., Alsaleh, H., Rodriguez-Flores, J. L., Eaaswarkhanth, M., Al-Mulla, F. & Thanaraj, T. A., Dec 2021, In: Scientific Reports. 11, 1, 1091.Research output: Contribution to journal › Article › peer-review
Open Access -
Obesity and Prediabetes are Jointly Associated with Lipid Abnormalities Among Adolescents: A Cross-Sectional Study
Almari, M., Mohammad, A., Abubaker, J. & Ziyab, A. H., 2021, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 14, p. 345-353 9 p.Research output: Contribution to journal › Article › peer-review
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2020
A comprehensive germline variant and expression analyses of ACE2, TMPRSS2 and SARS-CoV-2 activator FURIN genes from the Middle East: Combating SARS-CoV-2 with precision medicine
Al-Mulla, F., Mohammad, A., Al Madhoun, A., Haddad, D., Ali, H., Eaaswarkhanth, M., John, S. E., Nizam, R., Channanath, A., Abu-Farha, M., Ahmad, R., Abubaker, J. & Thanaraj, A. T., 16 May 2020, In: BioRxiv. BIORXIV/2020/099176, p. 1 to 28 28 p.Research output: Contribution to journal › Article
Open Access -
Adaptive fitness advantage in ancestors: a major health risk to a present-day Arab population
Eaaswarkhanth, M., Campelo dos Santos, A. L., Gokcumen, O., Al-Mulla, F. & Thanaraj, A. T., 20 Apr 2020.Research output: Contribution to conference › Poster › peer-review
Open Access -
Adipose tissue gene expression of CXCL10 and CXCL11 modulates inflammatory markers in obesity: implications for metabolic inflammation and insulin resistance
Kochumon, S., Madhoun, A. A., Al-Rashed, F., Azim, R., Al-Ozairi, E., Al-Mulla, F. & Ahmad, R., 2020, In: Therapeutic Advances in Endocrinology and Metabolism. 11, p. 2042018820930902Research output: Contribution to journal › Article › peer-review
Open Access -
Adopting identification standards in the medical device supply chain
Abdulsalam, Y., Alhuwail, D. & Schneller, E. S., 1 Jan 2020, In: International Journal of Information Systems and Supply Chain Management. 13, 1, p. 1-14 14 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Adult Diabetes and Prediabetes Prevalence in Kuwait: Data from the Cross-Sectional Kuwait Diabetes Epidemiology Program
Alkandari, A., Alarouj, M., Elkum, N., Sharma, P., Sriraman, D., Abu-Farha, M., Al-Mulla, F., Tuomilehto, J. & Bennakhi, A., 2020, In: Journal of Clinical Medicine. 9:3420, doi:10.3390/jcm9113420Research output: Contribution to journal › Article › peer-review
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Atherogenic Index of Plasma (AIP) a Tool to Assess Changes in Cardiovascular Disease Risk Post Laparoscopic Sleeve Gastrectomy
Al Shawaf, E., Al-Ozairi, E., Al-Asfar, F., Mohammad, A., Al-Beloushi, S., Devarajan, S., Al-Mulla, F., Abubaker, J. & Arefanian, H., Aug 2020, In: Journal of Diabetes Research. 2020, doi.org/10.1155/2020/2091341, p. 2091341 2091341.Research output: Contribution to journal › Article › peer-review
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Clinical characteristics of coronavirus disease 2019 (COVID-19) patients in Kuwait
Alshukry, A., Ali, H., Ali, Y., Al-Taweel, T., Abu-Farha, M., AbuBaker, J., Devarajan, S., Dashti, A. A., Bandar, A., Taleb, H., Bader, A. A., Aly, N. Y., Al-Ozairi, E., Al-Mulla, F. & Abbas, M. B., Nov 2020, In: PloS one. 15, 11 November, e0242768.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Combination therapy with pioglitazone/exenatide improves beta-cell function and produces superior glycaemic control compared with basal/bolus insulin in poorly controlled type 2 diabetes: A 3-year follow-up of the Qatar study
Abdul-Ghani, M., Migahid, O., Megahed, A., DeFronzo, R. A., Al-Ozairi, E. & Jayyousiv, A., 2020, (Accepted/In press) In: Diabetes, Obesity and Metabolism.Research output: Contribution to journal › Article › peer-review
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Comparative Proteomic Analysis Identifies EphA2 as a Specific Cell Surface Marker for Wharton's Jelly-Derived Mesenchymal Stem Cells
Al Madhoun, A., Marafie, S. K., Haddad, D., Melhem, M., Abu-Farha, M., Ali, H., Sindhu, S., Atari, M. & Al-Mulla, F., 3 Sep 2020, In: International Journal of Molecular Sciences. 21, 17Research output: Contribution to journal › Article › peer-review
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Continuous Glucose Monitoring of Glycemic Variability During Fasting Post-Sleeve Gastrectomy
Al-Ozairi, E., El Samad, A., Al Kandari, J., Taghadom, E., Adam, S., le Roux, C. & Syed, A. A., 1 Oct 2020, In: Obesity Surgery. 30, 10, p. 3721-3729 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Correlation of circulating ANGPTL5 levels with obesity, high sensitivity C-reactive protein and oxidized low-density lipoprotein in adolescents
Hammad, M. M., Abu-Farha, M., Al-Taiar, A., Alam-Eldin, N., Al-Sabah, R., Shaban, L., Al-Mulla, F., Abubaker, J. & Rahman, A., 14 Apr 2020, In: Scientific Reports. 10, 1, p. 6330 6330.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Correlation profile of suppression of tumorigenicity 2 and/or interleukin-33 with biomarkers in the adipose tissue of individuals with different metabolic states
Hasan, A., Kochumon, S., Al Ozairi, E., Tuomilehto, J., Al-Mulla, F. & Ahmad, R., 20 Oct 2020, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.Research output: Contribution to journal › Article › peer-review
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Could the D614G substitution in the SARS-CoV-2 spike (S) protein be associated with higher COVID-19 mortality?
Eaaswarkhanth, M., Al Madhoun, A. & Al-Mulla, F., Jul 2020, In: International Journal of Infectious Diseases. 96, p. 459-460 2 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Citations (Scopus) -
Effect of sleeve gastrectomy on the expression of meteorin-like (METRNL) and Irisin (FNDC5) in muscle and brown adipose tissue and its impact on uncoupling proteins in diet-induced obesity rats
Jamal, M. H., Abu-Farha, M., Al-Khaledi, G., Al-Sabah, S., Ali, H., Cherian, P., Al-Khairi, I., AlOtaibi, F., Al-Ali, W., Bosso, M., Dsouza, C., Abubaker, J. & Al-Mulla, F., 31 Jul 2020, (E-pub ahead of print) In: Surgery for Obesity and Related Diseases.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance
Kochumon, S., Al Madhoun, A., Al-Rashed, F., Thomas, R., Sindhu, S., Al-Ozairi, E., Al-Mulla, F. & Ahmad, R., 1 Dec 2020, In: Scientific Reports. 10, 1, 16364.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients
Sindhu, S., Kochumon, S., Thomas, R., Bennakhi, A., Al-Mulla, F. & Ahmad, R., 16 Mar 2020, In: Cells. 9, 3Research output: Contribution to journal › Article › peer-review
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Erratum: Protocol for a randomised controlled trial to investigate the effect of home- And gym-based resistance exercise training on glycaemic control, body composition and muscle strength (Trials (2020) 21: 557 DOI: 10.1186/s13063-020-04480-2)
Al Ozairi, E., Alsaeed, D., Taliping, D., Jalali, M., El Samad, A., Mashankar, A., Taghadom, E., Guess, N., Gill, J. M. R., Sattar, N., Gray, C., Welsh, P. & Gray, S. R., 15 Jul 2020, In: Trials. 21, 1, 650.Research output: Contribution to journal › Comment/debate
Open Access -
Evaluating the accessibility of higher education institution websites in the State of Kuwait: empirical evidence
AlMeraj, Z., Boujarwah, F., Alhuwail, D. & Qadri, R., 2020, (Accepted/In press) In: Universal Access in the Information Society.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Fasting Blood Glucose and COVID-19 Severity: Nonlinearity Matters
Alahmad, B., Abdullah, A. S., Bennakhi, A., Al-Mulla, F. & Ali, H., Oct 2020, In: Diabetes Care. 43, 11Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Fetuin-a expression profile in mouse and human adipose tissue
Khadir, A., Kavalakatt, S., Madhu, D. & Tiss, A., 12 Mar 2020, In: Lipids in Health and Disease. 19, 1, 38.Research output: Contribution to journal › Review article › peer-review
Open Access -
Fine-scale population structure reveals high genetic heterogeneity of the Kuwaiti population in the Arabian Peninsula
Eaaswarkhanth, M., Pathak, A., Ongaro, L., Montinaro, F., Hebbar, P., Alsmadi, O., Metspalu, M., Al-Mulla, F. & Thanaraj, A. T., 23 Nov 2020, In: BioRxiv. BIORXIV/2020/393892, p. 1-18 18 p.Research output: Contribution to journal › Article
Open Access -
Fructose tolerance test in obese people with and without type 2 diabetes
Al-Ozairi, E., Rivard, C. J., Sanchez Lozada, L. G., Lanaspa, M. A., Bjornstad, P., Al Salem, D., Alhubail, A., Megahed, A., Kuwabara, M., Johnson, R. J. & Asad, R. A., 1 Mar 2020, In: Journal of Diabetes. 12, 3, p. 197-204 8 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
FTO Variant rs1421085 Associates With Increased Body Weight, Soft Lean Mass, and Total Body Water Through Interaction With Ghrelin and Apolipoproteins in Arab Population
Hebbar, P., Abu-Farha, M., Mohammad, A., Alkayal, F., Melhem, M., Abubaker, J., Al-Mulla, F. & Thanaraj, T. A., 31 Jan 2020, In: Frontiers in Genetics. 10, p. 1411 1411.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population
Hebbar, P., Abu-Farha, M., Alkayal, F., Nizam, R., Elkum, N., Melhem, M., John, S. E., Channanath, A., Abubaker, J., Bennakhi, A., Al-Ozairi, E., Tuomilehto, J., Pitkaniemi, J., Alsmadi, O., Al-Mulla, F. & Thanaraj, T. A., 13 Jan 2020, In: Scientific Reports. 10, 1, p. 152 152.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population
Hebbar, P., Abubaker, J. A., Abu-Farha, M., Alsmadi, O., Elkum, N., Alkayal, F., John, S. E., Channanath, A., Iqbal, R., Pitkaniemi, J., Tuomilehto, J., Sladek, R., Al-Mulla, F. & Thanaraj, T. A., 9 Sep 2020, (E-pub ahead of print) In: Human Genetics.Research output: Contribution to journal › Article › peer-review
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Genome-wide Selection Scan in an Arabian Peninsula Population Identifies a TNKS haplotype Linked to Metabolic Traits and Hypertension.
Eaaswarkhanth, M., Campelo dos Santos, A. L., Gokcumen, O., Al-Mulla, F. & Thanaraj, A. T., 17 Mar 2020, In: Genome Biology and Evolution. 12, 3, p. 77-87 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus)1 Downloads (Pure) -
Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication
Abdullah, A., Alkandari, A., Longenecker, J. C., Sriraman, D., Alkhatib, A., AlWotayan, R., Al Duwairi, Q. & Tuomilehto, J., 2020, In: Primary Care Diabetes. 14(4):311-316, 10.1016/j.pcd.2019.12.001Research output: Contribution to journal › Article › peer-review
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Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
Rodriguez-Martinez, A., Zhou, B., Sophiea, M. K., Bentham, J., Paciorek, C. J., Iurilli, M. LC., Carrillo-Larco, R. M., Bennett, J. E., Di Cesare, M., Taddei, C., Bixby, H., Stevens, G. A., Riley, L. M., Cowan, M. J., Savin, S., Danaei, G., Chirita-Emandi, A., Kengne, A. P., Khang, Y. H., Laxmaiah, A. & 1,342 others, , 7 Nov 2020, In: The Lancet. 396, 10261, p. 1511-1524 14 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Higher BDNF Levels in the Circulation is Associated with Angiogenesis, Inflammatory and Metabolic Biomarkers in Children
Hasan, A., Kochumon, S., Ali, S. & Mandani, F., 2020, (Accepted/In press).Research output: Contribution to conference › Poster › peer-review
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Higher binding affinity of Furin to SARS-CoV-2 spike (S) protein D614G could be associated with higher SARS-CoV-2 infectivity
Mohammad, A., Alshawaf, E., Marafie, S. K., Abu-Farha, M., Abubaker, J. & Al-Mulla, F., 16 Oct 2020, (E-pub ahead of print) In: International Journal of Infectious Diseases.Research output: Contribution to journal › Article › peer-review
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Identification and management of Lynch syndrome in the Middle East and North African countries: outcome of a survey in 12 countries
2020, (Accepted/In press) In: Familial Cancer.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of HLA‐C*16:46 allele in a Kuwaiti individual
Jacob, S., 1 Jan 2020, In: HLA. 95, 1, p. 71-72 2 p.Research output: Contribution to journal › Article › peer-review
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Impact of Diabetes in Patients Diagnosed With COVID-19
Abu-Farha, M., Al-Mulla, F., Thanaraj, T. A., Kavalakatt, S., Ali, H., Abdul Ghani, M. & Abubaker, J., 1 Dec 2020, In: Frontiers in Immunology. 11, 576818.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
23 Oct 2020, In: Science (New York, N.Y.). 370, 6515Research output: Contribution to journal › Article › peer-review
Open Access125 Citations (Scopus) -
Increased Plasma Levels of Adenylate Cyclase 8 and cAMP Are Associated with Obesity and Type 2 Diabetes: Results from a Cross-Sectional Study
Abdel-Halim, S. M., Al Madhoun, A., Nizam, R., Melhem, M., Cherian, P., Al-Khairi, I., Haddad, D., Abu-Farha, M., Abubaker, J., Bitar, M. S. & Al-Mulla, F., Sep 2020, In: Biology. 9, 9, p. 1-13 13 p., 244.Research output: Contribution to journal › Article › peer-review
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Increasing the Duration of Light Physical Activity Ameliorates Insulin Resistance Syndrome in Metabolically Healthy Obese Adults
Al-Rashed, F., Alghaith, A., Azim, R., AlMekhled, D., Thomas, R., Sindhu, S. & Ahmad, R., 11 May 2020, In: Cells. 9, 5Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes
Qaddoumi, M. G., Alanbaei, M., Hammad, M. M., Al Khairi, I., Cherian, P., Channanath, A., Thanaraj, T. A., Al-Mulla, F., Abu-Farha, M. & Abubaker, J., 10 Apr 2020, In: Scientific Reports. 10, 1, p. 6170 6170.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Late bedtime and dental caries incidence in Kuwaiti children: A longitudinal multilevel analysis
Alqaderi, H., Tavares, M., Al-Mulla, F., Al-Ozairi, E. & Goodson, J. M., 2020, (Accepted/In press) In: Community Dentistry and Oral Epidemiology.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
LPS induces GM-CSF production by breast cancer MDA-MB-231 cells via long-chain acyl-CoA synthetase 1
Al-Rashed, F., Thomas, R., Al-Roub, A., Al-Mulla, F. & Ahmad, R., Oct 2020, In: Molecules. 25, 20, 4709.Research output: Contribution to journal › Article › peer-review
Open Access -
Maturity-onset diabetes of the young (MODY): a time to act. a time to act
Mohammad Abdullah Al-kandari, H., Mahmoud Yousef Alabdulrazzaq, D., Davidsson, L. & Al-Mulla, F., Jul 2020, In: The Lancet Diabetes and Endocrinology. 8, 7, p. 565-566 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort
Hammad, M. M., Abu-Farha, M., Hebbar, P., Cherian, P., Al Khairi, I., Melhem, M., Alkayal, F., Alsmadi, O., Thanaraj, T. A., Al-Mulla, F. & Abubaker, J., Jul 2020, In: Frontiers in Endocrinology. 11, p. 437 1 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Mediation effect of C-reactive protein in the relationship between abdominal obesity and intermediate hyperglycemia in Kuwaiti adolescents
Alqaderi, D. H., Al Ozairi, E., Bin-Hasan, S., Tavares, M., Goodson, J. M., AlSumait, A., Abu-Farha, M., Abubaker, J., Sriraman, D., AlMuhana, N. & Al-Mulla, F., 5 Nov 2020, In: Biomarkers in Medicine. 12 p., ISSN 1752-0363.Research output: Contribution to journal › Article › peer-review
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Method For Preventing Progression To Metabolic Syndrome
Al-Mulla, F., Nizam, R. & Al Madhoun, A., 4 Aug 2020, IPC No. US, Patent No. 10,731,219, B1, 19 Sep 2019Research output: Patent
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MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress
Sindhu, S., Akhter, N., Wilson, A., Thomas, R., Arefanian, H., Al Madhoun, A., Al-Mulla, F. & Ahmad, R., 29 Jul 2020, In: Cells. 9, 8Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α
Al-Rashed, F., Ahmad, Z., Thomas, R., Melhem, M., Snider, A., Obeid, L., Al-Mulla, F., Hannun, Y. & Ahmad, R., 1 Dec 2020, In: Scientific Reports. 10, 1, 16802.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Plasma Calprotectin Is Associated with Obesity and Systemic Inflammation in Children
Hasan, A., Kochumon, S. & Mohammad Abdullah Al-kandari, H., Jun 2020.Research output: Contribution to conference › Poster › peer-review
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Positively selected TNKS haplotype: from evolutionary advantage to the health risk in an Arabian Peninsula population
Eaaswarkhanth, M., Campelo dos Santos, A. L., Gokcumen, O., Al-Mulla, F. & Thanaraj, A. T., 6 Jun 2020.Research output: Contribution to conference › Poster › peer-review