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• 2020

  Protocol for a randomised controlled trial to investigate the effect of home- And gym-based resistance exercise training on glycaemic control, body composition and muscle strength

  Al Ozairi, E., Alsaeed, D., Alsaeed, D., Taliping, D., Jalali, M., Jalali, M., El Samad, A., Mashankar, A., Taghadom, E., Taghadom, E., Guess, N., Gill, J. M. R., Sattar, N., Gray, C., Welsh, P. & Gray, S. R., 22 Jun 2020, In: Trials. 21, 1, 557.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Resistance Training
  • Muscle Strength
  • Body Composition
  • Randomized Controlled Trials
  • Exercise

• Rabson–Mendenhall Syndrome in a brother-sister pair in Kuwait: Diagnosis and 5 year follow up

  Al-Kandari, H., Al-Abdulrazzaq, D., Al-Jaser, F., Al-Mulla, F. & Davidsson, L., 2020, (Accepted/In press) In: Primary Care Diabetes.

  Research output: Contribution to journal › Article › peer-review

• Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway

  Al-Rashed, F., Sindhu, S., Arefanian, H., Al Madhoun, A., Kochumon, S., Thomas, R., Al-Kandari, S., Alghaith, A., Jacob, T., Al-Mulla, F. & Ahmad, R., 12 Aug 2020, In: Cells. 9, 8

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hyperglycemia
  • Macrophages
  • Type 2 Diabetes Mellitus
  • Glucose
  • Interleukin-1
  1 Citation (Scopus)

• Repositioning of the global epicentre of non-optimal cholesterol

  Imperial College London, 4 Jun 2020, In: Nature. 582, 7810, p. 73-77 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • lipoprotein cholesterol
  • Southeastern Asia
  • Far East
  • Cholesterol
  • Income
  6 Citations (Scopus)

• RKIP & GSK3β: The interaction of two intracellular signaling network regulators and their role in cancer

  Bosso, M. & Al-Mulla, F., 5 Feb 2020, Prognostic and Therapeutic Applications of RKIP in Cancer. Elsevier, p. 147-173 27 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Role of Caveolin-1 in Diabetes and Its Complications

  Haddad, D., Al Madhoun, A., Nizam, R. & Al-Mulla, F., 28 Jan 2020, In: Oxidative Medicine and Cellular Longevity. 2020, p. 9761539 9761539 .

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Caveolin 1
  • Medical problems
  • Diabetes Complications
  • Signal transduction
  • Insulin
  4 Citations (Scopus)

• Skeletal muscle and metabolic health – how do we increase muscle mass and function in people with type 2 diabetes?

  Al Ozairi, E., AlRoudhan, D. D., Alsaeed, D., Voase, N., Hasan, A., Gill, J., Sattar, N., Welsh, P., Gray, C., Boonpor, J., Celis-Morales, C. & Gray, S., 2020, (Accepted/In press) In: Journal of Clinical Endocrinology and Metabolism.

  Research output: Contribution to journal › Review article › peer-review

• Soluble epoxide hydrolase 2 expression is elevated in obese humans and decreased by physical activity

  Khadir, A., Kavalakatt, S., Madhu, D., Cherian, P., Al-Mulla, F., Abubaker, J. & Tiss, A., 2 Mar 2020, In: International Journal of Molecular Sciences. 21, 6, 2056.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hydrolases
  • epoxy compounds
  • Epoxide Hydrolases
  • Endoplasmic Reticulum Stress
  • 3T3-L1 Cells
  1 Citation (Scopus)

• Soluble suppression of tumorigenicity 2 is directly correlated with glycated hemoglobin in individuals with an average glycaemia in the normal/prediabetes range.

  Hasan, A. & Al-Dhahi, W., 3 Aug 2020, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.

  Research output: Contribution to journal › Article › peer-review

• Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes

  Khadir, A., Kavalakatt, S., Madhu, D., Devarajan, S., Abubaker, J., Al-Mulla, F. & Tiss, A., 30 Jun 2020, In: Scientific Reports. 10, 1, p. 10635 10635.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Obesity
  • Exercise
  • Type 2 Diabetes Mellitus
  • Weights and Measures
  • Blood Pressure

• Stearic acid and tnf-α co-operatively potentiate mip-1α production in monocytic cells via myd88 independent tlr4/tbk/irf3 signaling pathway

  Kochumon, S., Arefanian, H., Azim, R., Shenouda, S., Jacob, T., Khalaf, N. A., Al-Rashed, F., Hasan, A., Sindhu, S., Al-Mulla, F. & Ahmad, R., Oct 2020, In: Biomedicines. 8, 10, p. 1-16 16 p., 403.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2

  Mohammad, A., Marafie, S. K., Alshawaf, E., Abu-Farha, M., Abubaker, J. & Al-Mulla, F., 5 Aug 2020, In: Life Sciences. 259, p. 118219

  Research output: Contribution to journal › Article › peer-review

  • angiotensin converting enzyme 2
  • Structural analysis
  • Betacoronavirus
  • Protein Binding
  • Severe Acute Respiratory Syndrome

• Targeted Metabolomics Analysis on Obstructive Sleep Apnea Patients after Multilevel Sleep Surgery

  Alterki, A., Joseph, S., Thanaraj, T. A., Al-Khairi, I., Cherian, P., Channanath, A., Sriraman, D., Ebrahim, M. A. K., Ibrahim, A., Tiss, A., Al-Mulla, F., Rahman, A. M. A., Abubaker, J. & Abu-Farha, M., 1 Sep 2020, In: Metabolites. 10, 9

  Research output: Contribution to journal › Article › peer-review

  • Metabolomics
  • Sleep
  • Obstructive Sleep Apnea
  • Surgery
  • Metabolites

• The Epidemiology of Depression and Diabetes Distress in Type 2 Diabetes in Kuwait

  Al-Ozairi, E., Al Ozairi, A., Blythe, C., Taghadom, E. & Ismail, K., 2020, In: Journal of Diabetes Research. 2020, 7414050.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The GLP-1 analog exendin-4 modulates HSP72 expression and ERK1/2 activity in BTC6 mouse pancreatic cells

  Madhu, D., Khadir, A., Hammad, M., Kavalakatt, S., Dehbi, M., Al-Mulla, F., Abubaker, J. & Tiss, A., Jul 2020, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1868, 7, p. 140426 140426.

  Research output: Contribution to journal › Article › peer-review

  • Exenatide
  • Glucagon-Like Peptide 1
  • Palmitic Acid
  • Heat-Shock Response
  • Phosphorylation

• The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation

  Abu-Farha, M., Ghosh, A., Al-Khairi, I., Madiraju, S. R. M., Abubaker, J. & Prentki, M., 2 Oct 2020, In: Progress in Lipid Research. 80, p. 101067

  Research output: Contribution to journal › Review article › peer-review

  • Lipoprotein Lipase
  • Angiopoietin-like Proteins
  • Modulation
  • Health
  • lipoprotein triglyceride

• The role of lipid metabolism in COVID-19 virus infection and as a drug target

  Abu-Farha, M., Thanaraj, T. A., Qaddoumi, M. G., Hashem, A., Abubaker, J. & Al-Mulla, F., 2 May 2020, In: International Journal of Molecular Sciences. 21, 10, 3544.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Lipid Metabolism
  • lipid metabolism
  • Lipids
  • infectious diseases
  • Coronavirus
  20 Citations (Scopus)

• The role of Raf kinase inhibitory protein in inflammation

  Shenouda, S., Ahmad, R., Bosso, M. & Al-Mulla, F., 2020, Prognostic and therapeutic applications of RKIP in cancer. p. 299-316 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• The state of mental digi-therapeutics: A systematic assessment of depression and anxiety apps available for Arabic speakers

  Alhuwail, D., Albaj, R., Ahmad, F. & Aldakheel, K., Mar 2020, In: International Journal of Medical Informatics. 135, 104056.

  Research output: Contribution to journal › Article › peer-review

  • Mental Health
  • Anxiety
  • Depression
  • Mental Disorders
  • Mobile Applications
  1 Citation (Scopus)

• The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19

  Bosso, M., Thanaraj, T. A., Abu-Farha, M., Alanbaei, M., Abubaker, J. & Al-Mulla, F., 11 Sep 2020, In: Molecular Therapy - Methods and Clinical Development. 18, p. 321-327 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • angiotensin converting enzyme 2
  • Coronavirus
  • Hypertension
  • Severe Acute Respiratory Syndrome
  • Angiotensin Receptor Antagonists
  10 Citations (Scopus)

• Top concerns of tweeters during the COVID-19 pandemic: Infoveillance Study

  Abd-Alrazaq, A., Alhuwail, D., Househ, M., Hai, M. & Shah, Z., 21 Apr 2020, In: Journal of Medical Internet Research. 22, 4, p. e19016 e19016.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Social Media
  • Pandemics
  • Racism
  • Economics
  • Organizations
  70 Citations (Scopus)
• 2019

  1871-P: Mir 103/107 Regulates Lipid Metabolism by Inhibiting Betatrophin/ANGPTL8

  ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., AL-MULLA, FAHD. & ABUBAKER, JEHAD., 2019, American Diabetes Association Inc.

  Research output: Other contribution › peer-review

• 268-LB: Investigating the Role of MPO and ANGPTL6 in Obesity and Diabetes and Their Potential Role in Wound Healing

  QADDOUMI, MOHAMMAD. G., ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., CHANNANATH, ARSHAD. MOHAMED., ALANBAEI, MUATH., ABUBAKER, JEHAD. & AL-MULLA, FAHD., 2019, American Diabetes Association Inc.

  Research output: Other contribution › peer-review

• 312-LB: Irisin, Meteorin-Like Protein, and Bone Remodeling Markers in T2D and Obesity

  ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., JAMAL, MOHAMMAD., AL-SABAH, SULEIMAN., Ali, H., DSOUZA, CAROL., ALOTAIBI, FATEMAH. KULAIB., AL-ALI, WALEED. & AL-KHALEDI, GHANIM. MOHAMMAD., 2019, American Diabetes Association Inc.

  Research output: Other contribution › peer-review

• A420 The Effect of Sleeve Gastrectomy on The Uncoupling Proteins in Animal Rat Model

  Jamal, M., Abu-Farha, M., Al-Khaledi, G., Al-Sabah, S., Ali, H., Al-Otaibi, F., Dsouza, C., Al-Ali, W. & Al-Mulla, F., 2019, In: Surgery for Obesity and Related Diseases. 15, 10, p. S171

  Research output: Contribution to journal › Article › peer-review

• Acsl1 regulates tnfα-induced gm-csf production by breast cancer mda-mb-231 cells

  Ahmad, R., Thomas, R., Al-Rashed, F., Akhter, N. & Al-Mulla, F., Oct 2019, In: Biomolecules. 9, 10, 555.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Granulocyte-Macrophage Colony-Stimulating Factor
  • Breast Neoplasms
  • Tumor Necrosis Factor-alpha
  • Phosphorylation
  • p38 Mitogen-Activated Protein Kinases
  5 Citations (Scopus)

• Acute effects of air pollution on mortality: A 17-year analysis in Kuwait

  Achilleos, S., Al Ozairi, E., Alahmad, B., Garshick, E., Neophytou, A. M., Bouhamra, W., Yassin, M. F. & Koutrakis, P., 1 May 2019, In: Environment International. 126, p. 476-483 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • visibility
  • atmospheric pollution
  • mortality
  • air quality
  • dust storm
  17 Citations (Scopus)

• Adipose tissue expression of CCL19 chemokine is positively associated with insulin resistance

  Kchumon, S., Salem Alrashed, F., Abu-Farha, M., Sriraman, D., Tuomilehto, J. & Ahmad, R., 1 Feb 2019, In: Diabetes/Metabolism Research and Reviews. 35, 2, p. e3087 e3087.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chemokine CCL19
  • Adipose Tissue
  • Insulin Resistance
  • Adiponectin
  • Interleukin-12
  6 Citations (Scopus)

• Angiopoietin-like proteins in multiple sclerosis

  Al-Temaimi, R., Cherian, P., Abu-Farha, M. & Alroughani, R., 15 May 2019, In: Journal of Neuroimmunology. 330, p. 31-34 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiopoietin-like Proteins
  • Multiple Sclerosis
  • Natalizumab
  • Fingolimod Hydrochloride
  • Lipid Metabolism
  1 Citation (Scopus)

• ANGPTL4 a predictive marker for diabetic nephropathy.

  Alshawaf, E., Abu-Farha, M., Sriraman, D., ALSAIRAFI, ZAHRA., Al Khairi, I., Cherian, P., Mohamed Ali Yaseen, H., Mathur, A., Al-Mulla, F., AlAttar, A. & Abubaker, J., 1 Jan 2019, In: Journal of Diabetes Research. 2019, p. 4943191 4943191.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Diabetic Nephropathies
  • Creatinine
  • Type 2 Diabetes Mellitus
  • Fasting
  • Biomarkers
  4 Citations (Scopus)

• A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations

  Hebbar, P., Abubaker, J. A., Abu-Farha, M., Tuomilehto, J., Al-Mulla, F. & Thanaraj, A. T., 1 Jan 2019, In: Frontiers in Endocrinology. 10, JAN, p. 8 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome
  • Population
  • Inbreeding
  • Kuwait
  • Fast Foods
  6 Citations (Scopus)

• A prospective study of the effect of fasting during the month of Ramadan on depression and diabetes distress in people with type 2 diabetes

  Al-Ozairi, E., AlAwadhi, M. M., Al-Ozairi, A., Taghadom, E. & Ismail, K., Jul 2019, In: Diabetes Research and Clinical Practice. 153, p. 145-149 5 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Assessing electronic health literacy in the state of Kuwait: Survey of internet users from an Arab state

  Alhuwail, D. & Abdulsalam, Y., May 2019, In: Journal of Medical Internet Research. 21, 5, e11174.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Kuwait
  • Health Literacy
  • Internet
  • Social Media
  • Literacy
  4 Citations (Scopus)

• Association between Adipose Tissue Interleukin-33 and Immunometabolic Markers in Individuals with Varying Degrees of Glycemia

  Hasan, A., Kochumon, S., Al Ozairi, E., Tuomilehto, J. & Ahmad, R., Apr 2019, In: Disease Markers. 2019, 7901062, p. 7901062 7901062.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interleukin-33
  • Tissue
  • Adipose Tissue
  • Medical problems
  • Prediabetic State
  2 Citations (Scopus)

• Audit of glycemic control in patients with type 1 diabetes referred to a pediatric clinic in a specialized center in Kuwait,

  Mahmoud Yousef Alabdulrazzaq, D., Al-Taiar, A., Shaltout, A., Davidsson, L. & Mohammad Abdullah Al-kandari, H., 1 Oct 2019, In: Diabetes Research and Clinical Practice. 156, 107827.

  Research output: Contribution to journal › Article › peer-review

  • Kuwait
  • Type 1 Diabetes Mellitus
  • Pediatrics
  • Subcutaneous Infusions
  • Hemoglobins

• Autoimmune signatures for prediction and diagnosis of autoimmune diabetes in Kuwait

  Jahromi, M., Al-Mulla, F. & Al-Ozairi, E., Jun 2019, In: Autoimmunity Reviews. 18, 6, p. 642-644 3 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Bariatric surgery modulates urinary levels of MicroRNAs involved in the regulation of renal function

  Alkandari, A., Ashrafian, H., Sathyapalan, T., Darzi, A., Holmes, E., Athanasiou, T., Atkin, S. L. & Gooderham, N. J., 1 Jan 2019, In: Frontiers in Endocrinology. 10, MAY, p. 319 319.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bariatric Surgery
  • MicroRNAs
  • Kidney
  • Urine
  • Transfection
  2 Citations (Scopus)

• Can structured education for women with gestational diabetes enhance knowledge and self-confidence in managing diabetes? A tertiary centre experience report.

  Gray, T., Prince, L., Venkarataman, H., Mahadasu, S., Meneni, D. & Aldibbiat, A. M., Mar 2019.

  Research output: Contribution to conference › Poster › peer-review

• Can weekly ‘foot alerts’ using a bespoke mobile app improve patient diabetic foot care knowledge and practices in Kuwait?

  Aldibbiat, A. M., Messenger, G., Al Ozairi, E., Hussain, I., Masoetsa, R. & Assi, M., 2019.

  Research output: Contribution to conference › Abstract › peer-review

  • Kuwait
  • Mobile Applications
  • Diabetic Foot
  • Foot
  • Podiatry

• Caveolin-1 Variant Is Associated With the Metabolic Syndrome in Kuwaiti Children (vol 9, 689, 2018)

  Nizam, R., Al-Ozairi, E., Goodson, J. M., Melhem, M., Davidsson, L., Alkhandari, H., Al Madhoun, A., Shamsah, S., Qaddoumi, M. & Alghanim, G., 2019, In: Frontiers in Genetics. 10

  Research output: Contribution to journal › Article › peer-review

• Corrigendum: Caveolin-1 Variant Is Associated With the Metabolic Syndrome in Kuwaiti Children: Caveolin-1 variant is associated with the metabolic syndrome in Kuwaiti children (Frontiers in Genetics ( 2018) 9 (689) DOI: 10.3389/fgene.2018.00689)

  Nizam, R., Al-Ozairi, E., Goodson, J. M., Melhem, M., Davidsson, L., Alkhandari, H., Al Madhoun, A., Shamsah, S., Qaddoumi, M., Alghanim, G., Alhasawi, N., Abu-Farha, M., Abubaker, J., Shi, P., Hartman, M-L., Tavares, M., Bitar, M., Ali, H., Arefanian, H., Devarajan, S. & 4 others, Al-Refaei, F., Alsmadi, O., Tuomilehto, J. & Al-Mulla, F., 1 Jan 2019, In: Frontiers in Genetics. 10, MAR, p. 221 1 p., 221.

  Research output: Contribution to journal › Comment/debate

  • Caveolin 1
  • Manuscripts
  • Metabolic Syndrome
  • Child
  • Names

• Dasman Diabetes Biobank Kuwait – Operations Overview

  Sriraman, D., Lopez, V., Mathur, A., Chandy, B. S., Shyamsundar, A., Jose, R. M., Vijayan, V., Abu-Farha, M. & Al-Mulla, F., 2019.

  Research output: Contribution to conference › Poster

• Diabetes impairs angiogenesis and induces endothelial cell senescence by up-regulating thrombospondin-CD47-dependent signaling

  Sami Bitar, M., 4 Feb 2019, In: International Journal of Molecular Sciences. 20, 3, 673.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • angiogenesis
  • Endothelial cells
  • Thrombospondins
  • Medical problems
  • Cellular Senescence
  6 Citations (Scopus)

• Dynamic oligomerization of hRAGE's transmembrane and cytoplasmic domains within SDS micelles

  Zamoon, J., Madhu, D. & Ahmed, I., 1 Jun 2019, In: International Journal of Biological Macromolecules. 130, p. 10-18 9 p.

  Research output: Contribution to journal › Article › peer-review

  • human AGER protein
  • Oligomerization
  • Micelles
  • Nuclear magnetic resonance spectroscopy
  • Oligomers

• Early immune mechanisms of neonatal porcine islet xenograft rejection

  Mok, D., Black, M., Gupta, N., Arefanian, H., Tredget, E. & Rayat, G. R., 1 Nov 2019, In: Xenotransplantation. 26, 6, e12546.

  Research output: Contribution to journal › Article › peer-review

  • Heterografts
  • Swine
  • Transplants
  • Heterologous Transplantation
  • Autoimmunity
  2 Citations (Scopus)

• Effect of Laparoscopic Sleeve Gastrectomy on Levels of Fractalkine (CX3CL1) in Obesity and Diabetes, 1-Year Follow-up

  Arefanian, H., Al Ozairi, E., Al-Asfar, F., Al-Beloushi, S., Alshawaf, E., Ahmad, R. & Al-Mulla, F., 2019.

  Research output: Contribution to conference › Poster › peer-review

• Experiences of people with type 1 diabetes fasting Ramadan following structured education: A qualitative study

  Alsaeed, D., Al Kandari, J. & Al Ozairi, E., Jul 2019, In: Diabetes Research and Clinical Practice. 153, p. 157-165 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Type 1 Diabetes Mellitus
  • Fasting
  • Education
  • Eating
  • Kuwait
  6 Citations (Scopus)

• Fasting during the holy month of Ramadan among older children and adolescents with type 1 diabetes in Kuwait

  Mohammed, K., Mahmoud Yousef Alabdulrazzaq, D., Fayed, A., El Busairi, E., Al Shawaf, F., AbdulRasoul, M. & Shaltout, A., 18 Jul 2019, In: Journal of Pediatric Endocrinology and Metabolism. 32, 8

  Research output: Contribution to journal › Article › peer-review

  3 Citations (Scopus)

• Fasting in Ramadan with type 1 diabetes: A dose adjustment for normal eating workshop in Kuwait

  Alsaeed, D., Al-Kandari, J. & Al-Ozairi, E., 1 Nov 2019, In: Health and Social Care in the Community. 27, 6, p. 1421-1429 9 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Genomic Revolution-Driven Cancer Research

  Meganathan, R. P. & Eaaswarkhanth, M., 2019, Essentials of Bioinformatics, Volume II: In Silico Life Sciences: Medicine. Shaik, N. A., Hakeem, K. R., Banaganapalli, B. & Elango, R. (eds.). 1 ed. Vol. II. p. 39 60 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review