Find Research outputs

Search results

• 2020

  Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway

  Al-Rashed, F., Sindhu, S., Arefanian, H., Al Madhoun, A., Kochumon, S., Thomas, R., Al-Kandari, S., Alghaith, A., Jacob, T., Al-Mulla, F. & Ahmad, R., 12 Aug 2020, In: Cells. 9, 8

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Repositioning of the global epicentre of non-optimal cholesterol

  Imperial College London, 4 Jun 2020, In: Nature. 582, 7810, p. 73-77 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Citations (Scopus)

• RKIP & GSK3β: The interaction of two intracellular signaling network regulators and their role in cancer

  Bosso, M. & Al-Mulla, F., 5 Feb 2020, Prognostic and Therapeutic Applications of RKIP in Cancer. Elsevier, p. 147-173 27 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Role of Caveolin-1 in Diabetes and Its Complications

  Haddad, D., Al Madhoun, A., Nizam, R. & Al-Mulla, F., 28 Jan 2020, In: Oxidative Medicine and Cellular Longevity. 2020, p. 9761539 9761539 .

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  8 Citations (Scopus)

• Skeletal Muscle and Metabolic Health: How Do We Increase Muscle Mass and Function in People with Type 2 Diabetes? How Do We Increase Muscle Mass and Function in People with Type 2 Diabetes?

  Al-Ozairi, E., Alsaeed, D., Alroudhan, D., Voase, N., Hasan, A., Gill, J. M. R., Sattar, N., Welsh, P., Gray, C. M., Boonpor, J., Celis-Morales, C. & Gray, S. R., 12 Nov 2020, In: Journal of Clinical Endocrinology and Metabolism. 106, 2, p. 309-317 9 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Citation (Scopus)

• Soluble epoxide hydrolase 2 expression is elevated in obese humans and decreased by physical activity

  Khadir, A., Kavalakatt, S., Madhu, D., Cherian, P., Al-Mulla, F., Abubaker, J. & Tiss, A., 2 Mar 2020, In: International Journal of Molecular Sciences. 21, 6, 2056.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Soluble suppression of tumorigenicity 2 is directly correlated with glycated hemoglobin in individuals with an average glycaemia in the normal/prediabetes range.

  Hasan, A. & Al-Dhahi, W., 3 Aug 2020, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.

  Research output: Contribution to journal › Article › peer-review

• Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes

  Khadir, A., Kavalakatt, S., Madhu, D., Devarajan, S., Abubaker, J., Al-Mulla, F. & Tiss, A., 30 Jun 2020, In: Scientific Reports. 10, 1, p. 10635 10635.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Stearic acid and tnf-α co-operatively potentiate mip-1α production in monocytic cells via myd88 independent tlr4/tbk/irf3 signaling pathway

  Kochumon, S., Arefanian, H., Azim, R., Shenouda, S., Jacob, T., Khalaf, N. A., Al-Rashed, F., Hasan, A., Sindhu, S., Al-Mulla, F. & Ahmad, R., Oct 2020, In: Biomedicines. 8, 10, p. 1-16 16 p., 403.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2

  Mohammad, A., Marafie, S. K., Alshawaf, E., Abu-Farha, M., Abubaker, J. & Al-Mulla, F., 5 Aug 2020, (E-pub ahead of print) In: Life Sciences. 259, p. 118219

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Targeted Metabolomics Analysis on Obstructive Sleep Apnea Patients after Multilevel Sleep Surgery

  Alterki, A., Joseph, S., Thanaraj, T. A., Al-Khairi, I., Cherian, P., Channanath, A., Sriraman, D., Ebrahim, M. A. K., Ibrahim, A., Tiss, A., Al-Mulla, F., Rahman, A. M. A., Abubaker, J. & Abu-Farha, M., 1 Sep 2020, In: Metabolites. 10, 9

  Research output: Contribution to journal › Article › peer-review

• The Epidemiology of Depression and Diabetes Distress in Type 2 Diabetes in Kuwait

  Al-Ozairi, E., Al Ozairi, A., Blythe, C., Taghadom, E. & Ismail, K., 2020, In: Journal of Diabetes Research. 2020, 7414050.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The GLP-1 analog exendin-4 modulates HSP72 expression and ERK1/2 activity in BTC6 mouse pancreatic cells

  Madhu, D., Khadir, A., Hammad, M., Kavalakatt, S., Dehbi, M., Al-Mulla, F., Abubaker, J. & Tiss, A., Jul 2020, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1868, 7, p. 140426 140426.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation

  Abu-Farha, M., Ghosh, A., Al-Khairi, I., Madiraju, S. R. M., Abubaker, J. & Prentki, M., 2 Oct 2020, (E-pub ahead of print) In: Progress in Lipid Research. 80, p. 101067

  Research output: Contribution to journal › Review article › peer-review
  5 Citations (Scopus)

• The role of lipid metabolism in COVID-19 virus infection and as a drug target

  Abu-Farha, M., Thanaraj, T. A., Qaddoumi, M. G., Hashem, A., Abubaker, J. & Al-Mulla, F., 2 May 2020, In: International Journal of Molecular Sciences. 21, 10, 3544.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  53 Citations (Scopus)

• The role of Raf kinase inhibitory protein in inflammation

  Shenouda, S., Ahmad, R., Bosso, M. & Al-Mulla, F., 2020, Prognostic and therapeutic applications of RKIP in cancer. p. 299-316 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• The state of mental digi-therapeutics: A systematic assessment of depression and anxiety apps available for Arabic speakers

  Alhuwail, D., Albaj, R., Ahmad, F. & Aldakheel, K., Mar 2020, In: International Journal of Medical Informatics. 135, 104056.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19

  Bosso, M., Thanaraj, T. A., Abu-Farha, M., Alanbaei, M., Abubaker, J. & Al-Mulla, F., 11 Sep 2020, In: Molecular Therapy - Methods and Clinical Development. 18, p. 321-327 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  25 Citations (Scopus)

• Top concerns of tweeters during the COVID-19 pandemic: Infoveillance Study

  Abd-Alrazaq, A., Alhuwail, D., Househ, M., Hai, M. & Shah, Z., 21 Apr 2020, In: Journal of Medical Internet Research. 22, 4, p. e19016 e19016.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  146 Citations (Scopus)
• 2019

  1871-P: Mir 103/107 Regulates Lipid Metabolism by Inhibiting Betatrophin/ANGPTL8

  ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., AL-MULLA, FAHD. & ABUBAKER, JEHAD., 2019, American Diabetes Association Inc.

  Research output: Other contribution › peer-review

• 268-LB: Investigating the Role of MPO and ANGPTL6 in Obesity and Diabetes and Their Potential Role in Wound Healing

  QADDOUMI, MOHAMMAD. G., ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., CHANNANATH, ARSHAD. MOHAMED., ALANBAEI, MUATH., ABUBAKER, JEHAD. & AL-MULLA, FAHD., 2019, American Diabetes Association Inc.

  Research output: Other contribution › peer-review

• 312-LB: Irisin, Meteorin-Like Protein, and Bone Remodeling Markers in T2D and Obesity

  ABU-FARHA, MOHAMED., CHERIAN, PREETHI. THOMAS., AL KHAIRI, IRINA., JAMAL, MOHAMMAD., AL-SABAH, SULEIMAN., Ali, H., DSOUZA, CAROL., ALOTAIBI, FATEMAH. KULAIB., AL-ALI, WALEED. & AL-KHALEDI, GHANIM. MOHAMMAD., 2019, American Diabetes Association Inc.

  Research output: Other contribution › peer-review

• A420 The Effect of Sleeve Gastrectomy on The Uncoupling Proteins in Animal Rat Model

  Jamal, M., Abu-Farha, M., Al-Khaledi, G., Al-Sabah, S., Ali, H., Al-Otaibi, F., Dsouza, C., Al-Ali, W. & Al-Mulla, F., 2019, In: Surgery for Obesity and Related Diseases. 15, 10, p. S171

  Research output: Contribution to journal › Article › peer-review

• Acsl1 regulates tnfα-induced gm-csf production by breast cancer mda-mb-231 cells

  Ahmad, R., Thomas, R., Al-Rashed, F., Akhter, N. & Al-Mulla, F., Oct 2019, In: Biomolecules. 9, 10, 555.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Acute effects of air pollution on mortality: A 17-year analysis in Kuwait

  Achilleos, S., Al Ozairi, E., Alahmad, B., Garshick, E., Neophytou, A. M., Bouhamra, W., Yassin, M. F. & Koutrakis, P., 1 May 2019, In: Environment international. 126, p. 476-483 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Citations (Scopus)

• Adipose tissue expression of CCL19 chemokine is positively associated with insulin resistance

  Kchumon, S., Salem Alrashed, F., Abu-Farha, M., Sriraman, D., Tuomilehto, J. & Ahmad, R., 1 Feb 2019, In: Diabetes/Metabolism Research and Reviews. 35, 2, p. e3087 e3087.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Angiopoietin-like proteins in multiple sclerosis

  Al-Temaimi, R., Cherian, P., Abu-Farha, M. & Alroughani, R., 15 May 2019, In: Journal of Neuroimmunology. 330, p. 31-34 4 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• ANGPTL4 a predictive marker for diabetic nephropathy.

  Alshawaf, E., Abu-Farha, M., Sriraman, D., ALSAIRAFI, ZAHRA., Al Khairi, I., Cherian, P., Mohamed Ali Yaseen, H., Mathur, A., Al-Mulla, F., AlAttar, A. & Abubaker, J., 1 Jan 2019, In: Journal of Diabetes Research. 2019, p. 4943191 4943191.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations

  Hebbar, P., Abubaker, J. A., Abu-Farha, M., Tuomilehto, J., Al-Mulla, F. & Thanaraj, A. T., 1 Jan 2019, In: Frontiers in Endocrinology. 10, JAN, p. 8 1 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• A prospective study of the effect of fasting during the month of Ramadan on depression and diabetes distress in people with type 2 diabetes

  Al-Ozairi, E., AlAwadhi, M. M., Al-Ozairi, A., Taghadom, E. & Ismail, K., Jul 2019, In: Diabetes Research and Clinical Practice. 153, p. 145-149 5 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Assessing electronic health literacy in the state of Kuwait: Survey of internet users from an Arab state

  Alhuwail, D. & Abdulsalam, Y., May 2019, In: Journal of Medical Internet Research. 21, 5, e11174.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Association between Adipose Tissue Interleukin-33 and Immunometabolic Markers in Individuals with Varying Degrees of Glycemia

  Hasan, A., Kochumon, S., Al Ozairi, E., Tuomilehto, J. & Ahmad, R., Apr 2019, In: Disease Markers. 2019, 7901062, p. 7901062 7901062.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Audit of glycemic control in patients with type 1 diabetes referred to a pediatric clinic in a specialized center in Kuwait,

  Mahmoud Yousef Alabdulrazzaq, D., Al-Taiar, A., Shaltout, A., Davidsson, L. & Mohammad Abdullah Al-kandari, H., 1 Oct 2019, In: Diabetes Research and Clinical Practice. 156, 107827.

  Research output: Contribution to journal › Article › peer-review

• Autoimmune signatures for prediction and diagnosis of autoimmune diabetes in Kuwait

  Jahromi, M., Al-Mulla, F. & Al-Ozairi, E., Jun 2019, In: Autoimmunity Reviews. 18, 6, p. 642-644 3 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Bariatric surgery modulates urinary levels of MicroRNAs involved in the regulation of renal function

  Alkandari, A., Ashrafian, H., Sathyapalan, T., Darzi, A., Holmes, E., Athanasiou, T., Atkin, S. L. & Gooderham, N. J., 1 Jan 2019, In: Frontiers in Endocrinology. 10, MAY, p. 319 319.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Can structured education for women with gestational diabetes enhance knowledge and self-confidence in managing diabetes? A tertiary centre experience report.

  Gray, T., Prince, L., Venkarataman, H., Mahadasu, S., Meneni, D. & Aldibbiat, A. M., Mar 2019.

  Research output: Contribution to conference › Poster › peer-review

• Can weekly ‘foot alerts’ using a bespoke mobile app improve patient diabetic foot care knowledge and practices in Kuwait?

  Aldibbiat, A. M., Messenger, G., Al Ozairi, E., Hussain, I., Masoetsa, R. & Assi, M., 2019, (E-pub ahead of print).

  Research output: Contribution to conference › Abstract › peer-review

• Caveolin-1 Variant Is Associated With the Metabolic Syndrome in Kuwaiti Children (vol 9, 689, 2018)

  Nizam, R., Al-Ozairi, E., Goodson, J. M., Melhem, M., Davidsson, L., Alkhandari, H., Al Madhoun, A., Shamsah, S., Qaddoumi, M. & Alghanim, G., 2019, In: Frontiers in Genetics. 10

  Research output: Contribution to journal › Article › peer-review

• Corrigendum: Caveolin-1 Variant Is Associated With the Metabolic Syndrome in Kuwaiti Children: Caveolin-1 variant is associated with the metabolic syndrome in Kuwaiti children (Frontiers in Genetics ( 2018) 9 (689) DOI: 10.3389/fgene.2018.00689)

  Nizam, R., Al-Ozairi, E., Goodson, J. M., Melhem, M., Davidsson, L., Alkhandari, H., Al Madhoun, A., Shamsah, S., Qaddoumi, M., Alghanim, G., Alhasawi, N., Abu-Farha, M., Abubaker, J., Shi, P., Hartman, M-L., Tavares, M., Bitar, M., Ali, H., Arefanian, H., Devarajan, S. & 4 others, Al-Refaei, F., Alsmadi, O., Tuomilehto, J. & Al-Mulla, F., 1 Jan 2019, In: Frontiers in Genetics. 10, MAR, p. 221 1 p., 221.

  Research output: Contribution to journal › Comment/debate

• Dasman Diabetes Biobank Kuwait – Operations Overview

  Sriraman, D., Lopez, V., Mathur, A., Chandy, B. S., Shyamsundar, A., Jose, R. M., Vijayan, V., Abu-Farha, M. & Al-Mulla, F., 2019.

  Research output: Contribution to conference › Poster

• Diabetes impairs angiogenesis and induces endothelial cell senescence by up-regulating thrombospondin-CD47-dependent signaling

  Sami Bitar, M., 4 Feb 2019, In: International Journal of Molecular Sciences. 20, 3, 673.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Citations (Scopus)

• Dynamic oligomerization of hRAGE's transmembrane and cytoplasmic domains within SDS micelles

  Zamoon, J., Madhu, D. & Ahmed, I., 1 Jun 2019, In: International Journal of Biological Macromolecules. 130, p. 10-18 9 p.

  Research output: Contribution to journal › Article › peer-review

• Early immune mechanisms of neonatal porcine islet xenograft rejection

  Mok, D., Black, M., Gupta, N., Arefanian, H., Tredget, E. & Rayat, G. R., 1 Nov 2019, In: Xenotransplantation. 26, 6, e12546.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Effect of Laparoscopic Sleeve Gastrectomy on Levels of Fractalkine (CX3CL1) in Obesity and Diabetes, 1-Year Follow-up

  Arefanian, H., Al Ozairi, E., Al-Asfar, F., Al-Beloushi, S., Alshawaf, E., Ahmad, R. & Al-Mulla, F., 2019.

  Research output: Contribution to conference › Poster › peer-review

• Experiences of people with type 1 diabetes fasting Ramadan following structured education: A qualitative study

  Alsaeed, D., Al Kandari, J. & Al Ozairi, E., Jul 2019, In: Diabetes Research and Clinical Practice. 153, p. 157-165 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Fasting during the holy month of Ramadan among older children and adolescents with type 1 diabetes in Kuwait

  Mohammed, K., Mahmoud Yousef Alabdulrazzaq, D., Fayed, A., El Busairi, E., Al Shawaf, F., AbdulRasoul, M. & Shaltout, A., 18 Jul 2019, In: Journal of Pediatric Endocrinology and Metabolism. 32, 8

  Research output: Contribution to journal › Article › peer-review

  3 Citations (Scopus)

• Fasting in Ramadan with type 1 diabetes: A dose adjustment for normal eating workshop in Kuwait

  Alsaeed, D., Al-Kandari, J. & Al-Ozairi, E., 1 Nov 2019, In: Health and Social Care in the Community. 27, 6, p. 1421-1429 9 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Genomic Revolution-Driven Cancer Research

  Meganathan, R. P. & Eaaswarkhanth, M., 2019, Essentials of Bioinformatics, Volume II: In Silico Life Sciences: Medicine. Shaik, N. A., Hakeem, K. R., Banaganapalli, B. & Elango, R. (eds.). 1 ed. Vol. II. p. 39 60 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Glucose-Mediated Glucose Disposal at Baseline Insulin Is Impaired in IFG

  Alatrach, M., Agyin, C., Mehta, R., Adams, J., DeFronzo, R. A. & Abdulghani, M., 1 Jan 2019, In: The Journal of clinical endocrinology and metabolism. 104, 1, p. 163-171 9 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Higher Levels of ANGPTL5 in the Circulation of Subjects With Obesity and Type 2 Diabetes Are Associated With Insulin Resistance

  Alghanim, G., Qaddoumi, M. G., Alhasawi, N., Cherian, P., Al-Khairi, I., Nizam, R., Alkayal, F., Alanbaei, M., Tuomilehto, J., Abubaker, J., Abu-Farha, M. & Al-Mulla, F., 1 Jan 2019, In: Frontiers in Endocrinology. 10, p. 495 1 p., 495.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)