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2018

Trainee-led Mentorship scheme for Foundation Doctors: Trainees perspective and views.

Leng, O. & Aldibbiat, A. M., 2018.

Research output: Contribution to conferenceAbstract

Trends in asthma hospital admissions and mortality in Kuwait, 2000-2014: A national retrospective observational study

H M Ziyab, A. & Abul, A. T., 1 May 2018, In : BMJ Open. 8, 5, e021244.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Volumetric comparison of autogenous bone and tissue-engineered bone replacement materials in alveolar cleft repair: a systematic review and meta-analysis

Kamal, M., H M Ziyab, A., Bartella, A., Mitchell, D., Al-Asfour, A., Hölzle, F., Kessler, P. & Lethaus, B., 1 Jul 2018, In : British Journal of Oral and Maxillofacial Surgery. 56, 6, p. 453-462 10 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

White blood cell subpopulation changes and prevalence of neutropenia among Arab diabetic patients attending Dasman Diabetes Institute in Kuwait

Ali, F., Alsayegh, F., Sharma, P., Waheedi, M., Bayoud, T. & Alrefai, F., 1 Mar 2018, In : PloS one. 13, 3, 193920.

Research output: Contribution to journalArticle

Open Access

A high rate of novel CYP11B1 mutations in Saudi Arabia

Alzahrani, A. S., Alswailem, M. M., Murugan, A. K., Saqer Hamad Alhmaidah, D., Capper, C. P., Auchus, R. J., Qasem, E., Alzahrani, O. S., Al-Sagheir, A. & Bin-Abbas, B., 1 Nov 2017, In : Journal of Steroid Biochemistry and Molecular Biology. 174, p. 217-224 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2 Citations (Scopus)

Anemia in diabetes: Experience of a single treatment center in Kuwait

Alsayegh, F., Waheedi, M., Bayoud, T., Al Hubail, A., Al-Refaei, F. & Sharma, P., 1 Aug 2017, In : Primary Care Diabetes. 11, 4, p. 383-388 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

ANGPTL8 (betatrophin) role in diabetes and metabolic diseases

Abu-Farha, M., Abubaker, J. & Tuomilehto, J., 1 Nov 2017, In : Diabetes/Metabolism Research and Reviews. 33, 8, e2919.

Research output: Contribution to journalReview article

22 Citations (Scopus)

A pilot study to evaluate the effect of Sudarshan Kriya Yoga (SKY) on the quality of life and anxiety of type 2 diabetic patients

Shiju, R., Thomas, D., Ali, S., Sriraman, D., Mahmoud Kamkar, M., Al-Arouj, M., Tuomilehto, J. & Bennakhi, A., 2017.

Research output: Contribution to conferencePoster

Application of High-Dimensional Statistics and Network Based Visualization Techniques on Arab Diabetes and Obesity Data

Mall, R., Rawi, R., Ullah, E., Kunji, K., Khadir, A., Tiss, A., Abubaker, J., Kulinski, M. A., Ramzi, M. M. & Bensmail, H., 2017, In : Journal of Health & Medical Informatics. 8, 2, p. 2

Research output: Contribution to journalArticle

Open Access

A pragmatic lifestyle modification programme reduces the incidence of predictors of cardio-metabolic disease and dysglycaemia in a young healthy urban South Asian population: A randomised controlled trial

Wijesuriya, M., Fountoulakis, N., Guess, N., Banneheka, S., Vasantharajah, L., Gulliford, M., Viberti, G., Gnudi, L. & Karalliedde, J., 30 Aug 2017, In : BMC Medicine. 15, 1, 146.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Assessment of plasma biomarkers for their association with Multiple Sclerosis progression

Jacob, S., Al-Kandari, A., Alroughani, R. & Al-Temaimi, R., 15 Apr 2017, In : Journal of Neuroimmunology. 305, p. 5-8 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Cardiovascular disease and type 2 diabetes: Has the dawn of a new era arrived?

Abdulghani, M., DeFronzo, R. A., Del Prato, S., Chilton, R., Singh, R. & Ryder, R. E. J., 1 Jul 2017, In : Diabetes care. 40, 7, p. 813-820 8 p.

Research output: Contribution to journalReview article

43 Citations (Scopus)

Cell viability Analysis to compare different protocols for Peripheral Blood Mono-nuclear Cell isolation.

Mathur, A., Sriraman, D., Lopez, V., Chandy, B. S., Shyamsundar, A., Jose, R. M., Vijayan, V., Mahmoud Kamkar, M. & Tuomilehto, J., 2017.

Research output: Contribution to conferencePoster

Combination Therapy with Exenatide Plus Pioglitazone Versus Basal/Bolus Insulin in Patients with Poorly Controlled Type 2 Diabetes on Sulfonylurea Plus Metformin: The Qatar Study

Abdulghani, M., Migahid, O., Megahed, A., Adams, J., Triplitt, C., DeFronzo, R. A., Zirie, M. & Jayyousi, A., 1 Mar 2017, In : Diabetes care. 40, 3, p. 325-331 7 p.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Complex adaptive forces shape skin barrier evolution in humans

Lin, Y. L., Eaaswarkhanth, M., PAJIC, PETAR., Xu, D., Rzhetskaya, M., Hayes, M. G., Blekhman, R., Jablonski, N. G. & Gokcumen, O., 21 Apr 2017, p. 264-264. 1 p.

Research output: Contribution to conferenceAbstract

Deciphering the role of ANGPTL8 and its Variants in Insulin Resistance and Lipid Metabolism by Proteomics

Abu-farha, M., Cherian, P., Al-khairi, I. & Abubaker, J., 2017, PROTEIN SCIENCE. Vol. 26. p. 175-175 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Decreased basal hepatic glucose uptake in impaired fasting glucose

Alatrach, M., Agyin, C., Adams, J., DeFronzo, R. A. & Abdulghani, M., 1 Jul 2017, In : Diabetologia. 60, 7, p. 1325-1332 8 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Decreased level of plasma fibroblast growth factor (FGF) acidic in people with Obstructive Sleep Apnea.

Abu-Farha, M., Cherian, P., Al Khairi, I., Sriraman, D., Mathur, A., Alhubail, A., Tuomilehto, J., Abubaker, J. & Al-Terki, A., 2017.

Research output: Contribution to conferencePoster

Dental pulp pluripotent-like stem cells (DPPSC), a new stem cell population with chromosomal stability and osteogenic capacity for biomaterials evaluation

Núñez-Toldrà, R., Martínez-Sarrà, E., Gil-Recio, C., Carrasco, M. Á., Al Madhoun, A., Montori, S. & Atari, M., 21 Apr 2017, In : BMC Cell Biology. 18, 1, 21.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Determinants of the increase in ketone concentration during SGLT2 inhibition in NGT, IFG and T2DM patients

Al Jobori, H., Daniele, G., Adams, J., Cersosimo, E., Triplitt, C., DeFronzo, R. A. & Abdulghani, M., 1 Jun 2017, In : Diabetes, Obesity and Metabolism. 19, 6, p. 809-813 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
3 Citations (Scopus)

Efficacy of exenatide plus pioglitazone vs basal/bolus insulin in T2DM patients with very high HbA1c

Abdulghani, M., Migahid, O., Megahed, A., DeFronzo, R. A., Zirie, M. & Jayyousi, A., 1 Jul 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 7, p. 2162-2170 9 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Empagliflozin and kinetics of renal glucose transport in healthy individuals and individuals with type 2 diabetes

Al-Jobori, H., Daniele, G., Cersosimo, E., Triplitt, C., Mehta, R., Norton, L., DeFronzo, R. A. & Abdulghani, M., 1 Jul 2017, In : Diabetes. 66, 7, p. 1999-2006 8 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

Ethnic differences in association of high body mass index with early onset of Type 1 diabetes - Arab ethnicity as case study

Channanath, A., Elkum, N., Mahmoud Yousef Alabdulrazzaq, D., Tuomilehto, J., Shaltout, A. & Thanaraj, A. T., 1 Apr 2017, In : PloS one. 12, 4, e0175728.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Exome sequencing for the differential diagnosis of ciliary chondrodysplasias: Example of a WDR35 mutation case and review of the literature

Antony, D., Nampoory, N., Bacchelli, C., Melhem, M., Wu, K., James, C. T., Beales, P. L., Hubank, M., Thomas, D., Mashankar, A., Behbehani, K., Schmidts, M. & Alsmadi, O., 1 Dec 2017, In : European Journal of Medical Genetics. 60, 12, p. 658-666 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Expression of the filaggrin gene in umbilical cord blood predicts eczema risk in infancy: A birth cohort study

H M Ziyab, A., Ewart, S., Lockett, G. A., Zhang, H., Arshad, H., Holloway, J. W. & Karmaus, W., 1 Sep 2017, In : Clinical and Experimental Allergy. 47, 9, p. 1185-1192 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Fasting Betatrophin, 1-year post Laparoscopic Sleeve Gastrectomy, a correlation to beta cell function & T2DM remission

Alshawaf, E., Al Ozairi, E., Al-Asfar, F. & Arefanian, H., 4 Dec 2017.

Research output: Contribution to conferencePoster

Functional foods and lifestyle approaches for diabetes prevention and management

Alkhatib, A., Tsang, C., Tiss, A., Bahorun, T., Arefanian, H., Barake, R., Khadir, A. & Tuomilehto, J., 1 Dec 2017, In : Nutrients. 9, 12, 1310.

Research output: Contribution to journalReview article

Open Access
46 Citations (Scopus)
Open Access
5 Citations (Scopus)

Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10

Zhang, W., Sartori, M. A., Makhnevych, T., Federowicz, K. E., Dong, X., Liu, L., Nim, S., Dong, A., Yang, J., Li, Y., Haddad, D., Ernst, A., Heerding, D., Tong, Y., Moffat, J. & Sidhu, S. S., 10 Nov 2017, In : Journal of Molecular Biology. 429, 22, p. 3546-3560 15 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Genetic association of ITPR3 SNP rs999943 with Type 2 Diabetes and related metabolic traits

Mahmoud Kamkar, M., Nizam, R. & Hasan, S., 16 Nov 2017, International Diabetes Federation 2017 Congress.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Genetic Risk Prediction using Family Health History Approach

Mahmoud Kamkar, M., Sriraman, D. & Thomas, D., 2017.

Research output: Contribution to conferencePoster

Genetic risk variants for metabolic traits in Arab populations

Hebbar, P., Elkum, N., Alkayal, F., John, S. E., Thanaraj, A. T. & Alsmadi, O., 20 Jan 2017, In : Scientific Reports. 7, 40988.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Genetic variants associated with warfarin dosage in Kuwaiti population

John, S. E., Antony, D., Eaaswarkhanth, M., Hebbar, P., Alkayal, F., Tuomilehto, J., Alsmadi, O. & Thanaraj, A. T., 1 Jun 2017, In : Pharmacogenomics. 18, 8

Research output: Contribution to journalArticle

3 Citations (Scopus)

Hepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance

Chen, H., Bai, J., Dong, F., Fang, H., Zhang, Y., Meng, W., Liu, B., Luo, Y., Liu, M., Bai, Y., Abdulghani, M., Li, R., Wu, J., Zeng, R., Zhou, Z., Dong, L. Q. & Liu, F., 1 Jun 2017, In : FASEB Journal. 31, 6, p. 2314-2326 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Higher level of Oxidized LDL circulation level in humans with Obstructive Sleep Apnea.

Al-Terki, A., Al Khairi, I., Sriraman, D., Shyamsundar, A., Warsam, S., Cherian, P., Abu-Farha, M., Tuomilehto, J. & Abubaker, J., 2017.

Research output: Contribution to conferencePoster

Identification of a rare germline NBN gene mutation by whole exome sequencing in a lung-cancer survivor from a large family with various types of cancer

Marafie, M. J., Dashti, M. & Al-Mulla, F., 1 Jul 2017, In : Familial Cancer. 16, 3, p. 389-394 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Impact of ethnicity and obesity on insulin resistance in two ethnic groups at very high risk of type 2 diabetes

Hassoun, S., Al-Atrash, M., Alkasim, M., Dabbous, Z., Mujahed, O., DeFronzo, R. A., Jayyousi, A., Zirie, M. & Abdulghani, M., 1 Jun 2017, In : Diabetes and Metabolism. 43, 3, p. 292-294 3 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Incidence of type 1 diabetes has doubled in Kuwaiti children 0-14 years over the last 20 years

Shaltout, A. A., Wake, D., Thanaraj, A. T., Omar, D. M., Mahmoud Yousef Alabdulrazzaq, D., Channanath, A., Mohammad Abdullah Al-kandari, H., Abdulrasoul, M., Miller, S., Conway, N., Tuomilehto, J. & Davidsson, L., 1 Dec 2017, In : Pediatric Diabetes. 18, 8, p. 761-766 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
Open Access
11 Citations (Scopus)

Increased Angiopoietin Like protein (ANGPTL) 4 and 8 circulation levels in people with Obstructive Sleep Apnea

Abubaker, J., Sriraman, D., Cherian, P., Al Khairi, I., Alhubail, A., Al Shaar, N., Tuomilehto, J. & Al-Terki, A., 2017.

Research output: Contribution to conferencePoster

Open Access
15 Citations (Scopus)

Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects

Eldor, R., Norton, L., Fourcaudot, M., Galindo, C., DeFronzo, R. A. & Abdulghani, M., 1 Dec 2017, In : PloS one. 12, 12, e0188208.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Inducible CTCF insulator delays the IgH 3' regulatory region-mediated activation of germline promoters and alters class switching

Braikia, F. Z., Oudinet, C., Haddad, D., Oruc, Z., Orlando, D., Dauba, A., Le Bert, M. L. & Khamlichi, A. A., 6 Jun 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 23, p. 6092-6097 6 p.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Infant and young child feeding patterns in Kuwait: Results of a cross-sectional survey

Carballo, M., Khatoon, N., Maclean, E. C., Al-Hamad, N., Mohammad, A., Al-Wotayan, R. & Abraham, S., 1 Aug 2017, In : Public Health Nutrition. 20, 12, p. 2201-2207 7 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Inhibition of renal sodium-glucose cotransport with empagliflozin lowers fasting plasma glucose and improves β-cell function in subjects with impaired fasting glucose

Abdulghani, M., Al Jobori, H., Daniele, G., Adams, J., Cersosimo, E., Triplitt, C. & DeFronzo, R. A., 1 Sep 2017, In : Diabetes. 66, 9, p. 2495-2502 8 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Insulin-associated weight gain in obese type 2 diabetes mellitus patients: What can be done?

Brown, A., Guess, N., Dornhorst, A., Taheri, S. & Frost, G., 1 Dec 2017, In : Diabetes, Obesity and Metabolism. 19, 12, p. 1655-1668 14 p.

Research output: Contribution to journalReview article

12 Citations (Scopus)