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2017
Decreased level of plasma fibroblast growth factor (FGF) acidic in people with Obstructive Sleep Apnea.
Abu-Farha, M., Cherian, P., Al Khairi, I., Sriraman, D., Mathur, A., Alhubail, A., Tuomilehto, J., Abubaker, J. & Al-Terki, A., 2017.Research output: Contribution to conference › Poster
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Dental pulp pluripotent-like stem cells (DPPSC), a new stem cell population with chromosomal stability and osteogenic capacity for biomaterials evaluation
Núñez-Toldrà, R., Martínez-Sarrà, E., Gil-Recio, C., Carrasco, M. Á., Al Madhoun, A., Montori, S. & Atari, M., 21 Apr 2017, In: BMC Cell Biology. 18, 1, 21.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Determinants of the increase in ketone concentration during SGLT2 inhibition in NGT, IFG and T2DM patients
Al Jobori, H., Daniele, G., Adams, J., Cersosimo, E., Triplitt, C., DeFronzo, R. A. & Abdulghani, M., 1 Jun 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 809-813 5 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Dietary intake in people consuming a reduced-carbohydrate diet in the National Diet and Nutrition Survey
Guess, N., 1 Jun 2017, In: Journal of Human Nutrition and Dietetics. 30, 3, p. 360-368 9 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
DnaJ Heat Shock Protein Family (Hsp40) Member C27 (DNAJC27) is a Heat Shock 40 protein (HSP40) family member that is increased the in obese people
Al Khairi, I., Sriraman, D., Cherian, P., Tuomilehto, J., Abubaker, J. & Abu-Farha, M., 2017.Research output: Contribution to conference › Poster
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Effect of Laparoscopic Sleeve Gastrectomy on Leptin and its Receptor in Morbid Obesity and Diabetes, 1-Year Follow-up.
Al-Beloushi, S., Al-Asfar, F., Al Ozairi, E., Alshawaf, E., Kumari, S., Al-Hubail, A., Sabua, S., Tuomilehto, J. & Arefanian, H., 2017.Research output: Contribution to conference › Poster › peer-review
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Effect of Laparoscopic Sleeve Gastrectomy on lipid profile in morbidly obese and morbidly obese diabetic patients. A one year Dasman Diabetes Institute study.
Al-Asfar, F., Al Ozairi, E., Alshawaf, E., Al-Beloushi, S., Tuomilehto, J. & Arefanian, H., 2017.Research output: Contribution to conference › Poster › peer-review
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Efficacy of exenatide plus pioglitazone vs basal/bolus insulin in T2DM patients with very high HbA1c
Abdulghani, M., Migahid, O., Megahed, A., DeFronzo, R. A., Zirie, M. & Jayyousi, A., 1 Jul 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 7, p. 2162-2170 9 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Empagliflozin and kinetics of renal glucose transport in healthy individuals and individuals with type 2 diabetes
Al-Jobori, H., Daniele, G., Cersosimo, E., Triplitt, C., Mehta, R., Norton, L., DeFronzo, R. A. & Abdulghani, M., 1 Jul 2017, In: Diabetes. 66, 7, p. 1999-2006 8 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Citations (Scopus) -
Ethnic differences in association of high body mass index with early onset of Type 1 diabetes - Arab ethnicity as case study
Channanath, A., Elkum, N., Mahmoud Yousef Alabdulrazzaq, D., Tuomilehto, J., Shaltout, A. & Thanaraj, A. T., 1 Apr 2017, In: PloS one. 12, 4, e0175728.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Exome sequencing for the differential diagnosis of ciliary chondrodysplasias: Example of a WDR35 mutation case and review of the literature
Antony, D., Nampoory, N., Bacchelli, C., Melhem, M., Wu, K., James, C. T., Beales, P. L., Hubank, M., Thomas, D., Mashankar, A., Behbehani, K., Schmidts, M. & Alsmadi, O., 1 Dec 2017, In: European Journal of Medical Genetics. 60, 12, p. 658-666 9 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Expression of the filaggrin gene in umbilical cord blood predicts eczema risk in infancy: A birth cohort study
H M Ziyab, A., Ewart, S., Lockett, G. A., Zhang, H., Arshad, H., Holloway, J. W. & Karmaus, W., 1 Sep 2017, In: Clinical and Experimental Allergy. 47, 9, p. 1185-1192 8 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Fasting Betatrophin, 1-year post Laparoscopic Sleeve Gastrectomy, a correlation to beta cell function & T2DM remission
Alshawaf, E., Al Ozairi, E., Al-Asfar, F. & Arefanian, H., 4 Dec 2017.Research output: Contribution to conference › Poster › peer-review
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Functional foods and lifestyle approaches for diabetes prevention and management
Alkhatib, A., Tsang, C., Tiss, A., Bahorun, T., Arefanian, H., Barake, R., Khadir, A. & Tuomilehto, J., 1 Dec 2017, In: Nutrients. 9, 12, 1310.Research output: Contribution to journal › Review article › peer-review
Open Access74 Citations (Scopus) -
Functionally-focused algorithmic analysis of high resolution microarray-CGH genomic landscapes demonstrates comparable genomic copy number aberrations in MSI and MSS sporadic colorectal cancer
Mohamed Ali Yaseen, H., Sami Bitar, M., Al Madhoun, A., Marafie, M. & Al-Mulla, F., 1 Feb 2017, In: PloS one. 12, 2, e0171690.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10
Zhang, W., Sartori, M. A., Makhnevych, T., Federowicz, K. E., Dong, X., Liu, L., Nim, S., Dong, A., Yang, J., Li, Y., Haddad, D., Ernst, A., Heerding, D., Tong, Y., Moffat, J. & Sidhu, S. S., 10 Nov 2017, In: Journal of Molecular Biology. 429, 22, p. 3546-3560 15 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Genetic association of ITPR3 SNP rs999943 with Type 2 Diabetes and related metabolic traits
Mahmoud Kamkar, M., Nizam, R. & Hasan, S., 16 Nov 2017, International Diabetes Federation 2017 Congress.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Genetic Risk Prediction using Family Health History Approach
Mahmoud Kamkar, M., Sriraman, D. & Thomas, D., 2017.Research output: Contribution to conference › Poster
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Genetic risk variants for metabolic traits in Arab populations
Hebbar, P., Elkum, N., Alkayal, F., John, S. E., Thanaraj, A. T. & Alsmadi, O., 20 Jan 2017, In: Scientific Reports. 7, 40988.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
Genetic variants associated with warfarin dosage in Kuwaiti population
John, S. E., Antony, D., Eaaswarkhanth, M., Hebbar, P., Alkayal, F., Tuomilehto, J., Alsmadi, O. & Thanaraj, A. T., 1 Jun 2017, In: Pharmacogenomics. 18, 8Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Hepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance
Chen, H., Bai, J., Dong, F., Fang, H., Zhang, Y., Meng, W., Liu, B., Luo, Y., Liu, M., Bai, Y., Abdulghani, M., Li, R., Wu, J., Zeng, R., Zhou, Z., Dong, L. Q. & Liu, F., 1 Jun 2017, In: FASEB Journal. 31, 6, p. 2314-2326 13 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Higher level of Oxidized LDL circulation level in humans with Obstructive Sleep Apnea.
Al-Terki, A., Al Khairi, I., Sriraman, D., Shyamsundar, A., Warsam, S., Cherian, P., Abu-Farha, M., Tuomilehto, J. & Abubaker, J., 2017.Research output: Contribution to conference › Poster
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Identification of a rare germline NBN gene mutation by whole exome sequencing in a lung-cancer survivor from a large family with various types of cancer
Marafie, M. J., Dashti, M. & Al-Mulla, F., 1 Jul 2017, In: Familial Cancer. 16, 3, p. 389-394 6 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Impact of ethnicity and obesity on insulin resistance in two ethnic groups at very high risk of type 2 diabetes
Hassoun, S., Al-Atrash, M., Alkasim, M., Dabbous, Z., Mujahed, O., DeFronzo, R. A., Jayyousi, A., Zirie, M. & Abdulghani, M., 1 Jun 2017, In: Diabetes and Metabolism. 43, 3, p. 292-294 3 p.Research output: Contribution to journal › Letter › peer-review
3 Citations (Scopus) -
Incidence of type 1 diabetes has doubled in Kuwaiti children 0-14 years over the last 20 years
Shaltout, A. A., Wake, D., Thanaraj, A. T., Omar, D. M., Mahmoud Yousef Alabdulrazzaq, D., Channanath, A., Mohammad Abdullah Al-kandari, H., Abdulrasoul, M., Miller, S., Conway, N., Tuomilehto, J. & Davidsson, L., 1 Dec 2017, In: Pediatric Diabetes. 18, 8, p. 761-766 6 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Increased adipose tissue expression of IL-18R and its Ligand IL-18 associates with inflammation and insulin resistance in obesity
Ahmad, R., Thomas, R., Kchumon, S. & Sindhu, S., 1 Jan 2017, In: Immunity Inflammation and Disease. 5, 3, p. 318-335 18 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (Scopus) -
Increased Angiopoietin Like protein (ANGPTL) 4 and 8 circulation levels in people with Obstructive Sleep Apnea
Abubaker, J., Sriraman, D., Cherian, P., Al Khairi, I., Alhubail, A., Al Shaar, N., Tuomilehto, J. & Al-Terki, A., 2017.Research output: Contribution to conference › Poster
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Increased circulatory levels of fractalkine (CX3CL1) are associated with inflammatory chemokines and cytokines in individuals with type-2 diabetes
Sindhu, S., Akhter, N., Arefanian, H., Abu-AlRoub, A., Ali, S., Wilson, A., Al-Hubail, A., Al-Beloushi, S., Al-Zanki, S. & Ahmad, R., 4 Apr 2017, In: Journal of Diabetes and Metabolic Disorders. 16, 1, 15.Research output: Contribution to journal › Article › peer-review
Open Access19 Citations (Scopus) -
Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects
Eldor, R., Norton, L., Fourcaudot, M., Galindo, C., DeFronzo, R. A. & Abdulghani, M., 1 Dec 2017, In: PloS one. 12, 12, e0188208.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Inducible CTCF insulator delays the IgH 3' regulatory region-mediated activation of germline promoters and alters class switching
Braikia, F. Z., Oudinet, C., Haddad, D., Oruc, Z., Orlando, D., Dauba, A., Le Bert, M. L. & Khamlichi, A. A., 6 Jun 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 23, p. 6092-6097 6 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
Infant and young child feeding patterns in Kuwait: Results of a cross-sectional survey
Carballo, M., Khatoon, N., Maclean, E. C., Al-Hamad, N., Mohammad, A., Al-Wotayan, R. & Abraham, S., 1 Aug 2017, In: Public Health Nutrition. 20, 12, p. 2201-2207 7 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Inhibition of renal sodium-glucose cotransport with empagliflozin lowers fasting plasma glucose and improves β-cell function in subjects with impaired fasting glucose
Abdulghani, M., Al Jobori, H., Daniele, G., Adams, J., Cersosimo, E., Triplitt, C. & DeFronzo, R. A., 1 Sep 2017, In: Diabetes. 66, 9, p. 2495-2502 8 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Insulin-associated weight gain in obese type 2 diabetes mellitus patients: What can be done?
Brown, A., Guess, N., Dornhorst, A., Taheri, S. & Frost, G., 1 Dec 2017, In: Diabetes, Obesity and Metabolism. 19, 12, p. 1655-1668 14 p.Research output: Contribution to journal › Review article › peer-review
26 Citations (Scopus) -
Is it time to change the type 2 diabetes treatment paradigm? Yes! GLP-1 ras should replace metformin in the type 2 diabetes algorithm
Abdulghani, M. & DeFronzo, R. A., 1 Aug 2017, In: Diabetes care. 40, 8, p. 1121-1127 7 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Citations (Scopus) -
Medical and pharmacy students’ attitudes towards physician-pharmacist collaboration in Kuwait
Katoue, M. G., Awad, A. I., Al-Jarallah, A., Al Ozairi, E. & Schwinghammer, T. L., 1 Jul 2017, In: Pharmacy Practice. 15, 3, 1029.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
National Dasman Diabetes Biobank - A Research Horizon
Sriraman, D., Lopez, V., Mathur, A., Chandy, B., Shyamsundar, A., Jose, R. M., Vijayan, V., Shiju, R., AlKandari, S., Marimuthu, V., Mahmoud Kamkar, M. & Tuomilehto, J., 2017.Research output: Contribution to conference › Poster
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National Diabetes Biobank – An overview.
Sriraman, D., Lopez, V., Mathur, A., Chandy, B. S., Shyamsundar, A., Jose, R. M., Vijayan, V., Mahmoud Kamkar, M. & Tuomilehto, J., 2017.Research output: Contribution to conference › Poster
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Next-generation sequencing in familial breast cancer patients from Lebanon
Jalkh, N., Chouery, E., Haidar, Z., Khater, C., Atallah, D., Mohamed Ali Yaseen, H., Marafie, M. J., Al-Mulla, M. R., Al-Mulla, F. & Megarbane, A., 15 Feb 2017, In: BMC Medical Genomics. 10, 1, p. 1-12 12 p., 8.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus) -
NHS Diabetes Prevention Programme is vital but criteria need reviewing
Guess, N., 1 Jan 2017, In: BMJ (Online). 356, j993.Research output: Contribution to journal › Letter › peer-review
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Normal Reference Ranges for Pulmonary Artery Diameters in Preterm Infants
Abushaban, L., Vel, M. T., Rathinasamy, J. & Sharma, P., 1 Oct 2017, In: Pediatric Cardiology. 38, 7, p. 1377-1384 8 p.Research output: Contribution to journal › Article › peer-review
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Novel G6B gene variant causes familial autosomal recessive thrombocytopenia and anemia
Melhem, M., Abu-Farha, M., Antony, D., Al Madhoun, A., Bacchelli, C., Alkayal, F., Al khairi, I., John, S. E., Alomari, M., Beales, P. L. & Alsmadi, O., 1 Mar 2017, In: European Journal of Haematology. 98, 3, p. 218-227 10 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Optical coherence tomography segmentation analysis in relapsing remitting versus progressive multiple sclerosis
Behbehani, R., Al-Hassan, A. A., Al-Salahat, A., Sriraman, D., Oakley, J. D. & Alroughani, R., 1 Feb 2017, In: PloS one. 12, 2, e0172120.Research output: Contribution to journal › Article › peer-review
Open Access25 Citations (Scopus) -
Pam3CSK4 induces MMP-9 expression in human monocytic THP-1 cells
Salem Alrashed, F., Kchumon, S., Usmani, S., Sindhu, S. & Ahmad, R., 1 Jun 2017, In: Cellular Physiology and Biochemistry. 41, 5, p. 1993-2003 11 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
Pheochromocytoma in pregnancy: The art of balancing risks for an optimal outcome.
Alsharefi, A. & Aldibbiat, A. M., 2017.Research output: Contribution to conference › Poster › peer-review
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Pioglitazone improves left ventricular diastolic function in subjects with diabetes
Clarke, G. D., Solis-Herrera, C., Molina-Wilkins, M., Martinez, S., Merovci, A., Cersosimo, E., Chilton, R. J., Iozzo, P., Gastaldelli, A., Abdulghani, M. & DeFronzo, R. A., 1 Nov 2017, In: Diabetes care. 40, 11, p. 1530-1536 7 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Citations (Scopus) -
Pioglitazone inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytes
Shannon, C. E., Daniele, G., Galindo, C., Abdulghani, M., DeFronzo, R. A. & Norton, L., 1 Feb 2017, In: FEBS Journal. 284, 3, p. 451-465 15 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
Plasma and adipose tissue level of angiopoietin-like 7 (ANGPTL7) are increased in obesity and reduced after physical exercise
Abu-Farha, M., Cherian, P., Al khairi, I., Madhu, D., Tiss, A., Warsam, S., Alhubail, A., Sriraman, D., Al-Refaei, F. & Abubaker, J., 1 Mar 2017, In: PloS one. 12, 3, e0173024.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
PLXNA3 Variant rs5945430 is Associated with Severe Clinical Course in Male Multiple Sclerosis Patients
Qureshi, M., Hatem, M., Alroughani, R., Jacob, S. & Al-Temaimi, R. A., 1 Sep 2017, In: NeuroMolecular Medicine. 19, 2-3, p. 286-292 7 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Potential role of Abscisic acid (ABA) in protecting beta cell function under glucolipotoxicity conditions.
Alkayal, F., Arefanian, H., Alshawaf, E., Marafie, S. & Tiss, A., 2017.Research output: Contribution to conference › Poster › peer-review
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Prevalence and Risk Factors of Asthma, Rhinitis, and Eczema and Their Multimorbidity among Young Adults in Kuwait: A Cross-Sectional Study
H M Ziyab, A., 1 Jan 2017, In: BioMed Research International. 2017, 2184193.Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus)