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• 2016

  Ganglion cell analysis in acute optic neuritis

  Behbehani, R., Al-Moosa, A., Sriraman, D. & Alroughani, R., 1 Jan 2016, In: Multiple Sclerosis and Related Disorders. 5, p. 66-69 4 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Genome-wide differential expression reveals candidate genes involved in the pathogenesis of lupus and lupus nephritis

  Alfadhli, S., Ghanem, A. A. M. & Nizam, R., 1 Jan 2016, In: International Journal of Rheumatic Diseases. 19, 1, p. 55-64 10 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• GWA Study from Kuwait Highlights Junk DNA as a Potential Hotspot in Hypertension Research: 9th World Congress on Prevention of Diabetes and its Complications

  Nizam, R., Hebbar, P., Antony, DI., Alkayal, F., John, S. E., Thomas, D., Melhem, M., Tuomilehto, J., Thanaraj, A. T. & Alsmadi, O., Dec 2016, WCPD9 Abstracts. Suppl 6) 27 ed. Endocrine Practice, Vol. 22.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

• Hereditary angioedema in a Jordanian family with a novel missense mutation in the C1-inhibitor N-terminal domain

  Jaradat, S. A., Caccia, S., Rawashdeh, R., Melhem, M., Al-Hawamdeh, A., Carzaniga, T. & Haddad, H., 1 Mar 2016, In: Molecular Immunology. 71, p. 123-130 8 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Identification of 42 genes linked to stage II colorectal cancer metastatic relapse

  Al-Temaimi, R. A., Tan, T. Z., Marafie, M. J., Thiery, J. P., Quirke, P. & Al-Mulla, F., 1 May 2016, In: International Journal of Molecular Sciences. 17, 5, 598.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Identifying home care clinicians’ information needs for managing fall risks

  Alhuwail, D. & Koru, G., 1 Jan 2016, In: Applied Clinical Informatics. 7, 2, p. 211-226 16 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Impact of short-term exposure of antifungal agents on hemolysin activity of oral Candida dubliniensis isolates from Kuwait and Sri Lanka

  Ellepola, A. N. B., Jayathilake, J. A. M. S., Sharma, P. & Khan, Z. U., 1 Nov 2016, In: Journal of investigative and clinical dentistry. 7, 4, p. 424-430 7 p.

  Research output: Contribution to journal › Article › peer-review

• Improvements in stage of change correlate to changes in dietary intake and clinical outcomes in a 5-year lifestyle intervention in young high-risk Sri Lankans

  Guess, N., Vasantharajah, L., Gulliford, M., Viberti, G., Gnudi, L., Karalliedde, J. & Wijesuriya, M., 1 Sep 2016, In: Preventive Medicine. 90, p. 193-200 8 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Increased adipose tissue expression of TLR8 in obese individuals with or without type-2 diabetes: Significance in metabolic inflammation

  Ahmad, R., Kchumon, S., Thomas, R., Atizado, V. & Sindhu, S., 8 Dec 2016, In: Journal of Inflammation (United Kingdom). 13, 1, 38.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Citations (Scopus)

• Increased adipose tissue expression of TLR-8 in obese individuals with or without type-2 diabetes: Significance in metabolic inflammation

  Ahmad, R., Kochumon, S., Thomas, R., Atizado, V. & Sindhu, S., 2016, In: Journal of Inflammation (United Kingdom). 13

  Research output: Contribution to journal › Article › peer-review

• Increased ANGPTL3, 4 and ANGPTL8/betatrophin expression levels in obesity and T2D

  Abu-Farha, M., Al khairi, I., Cherian, P., Chandy, B., Sriraman, D., Alhubail, A., Al-Refaei, F., AlTerki, A. & Abubaker, J., 13 Oct 2016, In: Lipids in Health and Disease. 15, 1, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  40 Citations (Scopus)

• INCREASED CIRCULATION LEVEL OF ANGPTL8/BETATROPHIN AND ANGPTL4 IN HYPERTENSION

  Qaddoumi, M. G., Al Khairi, I., Cherian, P., Alanbaei, M., Abubaker, J. & Abu-Farha, M., 2016, In: Endocrine Practice. 22, p. 10 1 p.

  Research output: Contribution to journal › Article › peer-review

• Increased expression of IL-18R and IL-18 in the adipose tissue is associated with insulin resistance (HOMA-IR) in obesity

  Kochumon, S., Thomas, R., Sindhu, S. & Ahmad, R., 2016.

  Research output: Contribution to conference › Poster › peer-review

• Increased expression of IRF-5 in the adipose tissue in obesity: Implication in metabolic inflammation

  Thomas, R., Kochumon, S., Ahmad, R. & Sindhu, S., 1 May 2016, In: Journal of Immunology. (1 Supplement) 124 , 196 , p. 51 51 p.

  Research output: Contribution to journal › Article › peer-review

• INCREASED PLASMA LEVEL OF ANGPTL3, 4 AND 8 IN OBESITY AND T2D

  AlTerki, A., Abu-Farha, M., Al-Khairi, I., Cherian, P., Chandy, B., Sriraman, D., Alhubail, A., Al-Refaei, F. & Abubaker, J., 2016, In: Endocrine Practice. 22, p. 23 1 p.

  Research output: Contribution to journal › Article › peer-review

• Influence of MX1 promoter rs2071430 G/T polymorphism on susceptibility to systemic lupus erythematosus

  AlFadhli, S., Al-Mutairi, M., Al Tameemi, B. & Nizam, R., 1 Mar 2016, In: Clinical Rheumatology. 35, 3, p. 623-629 7 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Influence of sex on P300: An event-related potential electrophysiological study

  KH H Bourisly, A. & Pothen, A., 28 Jan 2016, In: NeuroReport. 27, 3, p. 172-179 8 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Investigating the Challenges and Opportunities in Home Care to Facilitate Effective Information Technology Adoption

  Koru, G., Alhuwail, D., Topaz, M., Norcio, A. F. & Mills, M. E., 1 Jan 2016, In: Journal of the American Medical Directors Association. 17, 1, p. 53-58 6 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• IRF3 promotes adipose inflammation and insulin resistance and represses browning

  Kumari, M., Wang, X., Lantier, L., Lyubetskaya, A., Eguchi, J., Kang, S., Tenen, D., Roh, H. C., Kong, X., Kazak, L., Ahmad, R. & Rosen, E. D., 1 Aug 2016, In: Journal of Clinical Investigation. 126, 8, p. 2839-2854 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  74 Citations (Scopus)

• Ketoacidosis at first presentation of type 1 diabetes mellitus among children: A study from Kuwait

  Shaltout, A. A., Channanath, A., Thanaraj, A. T., Omar, D., Abdulrasoul, M., Zanaty, N., Almahdi, M., Mohammad Abdullah Al-kandari, H., Mahmoud Yousef Alabdulrazzaq, D., D'Mello, L., Mandani, F., Alanezi, A., AlBasiry, E. & Alkhawari, M., 22 Jun 2016, In: Scientific Reports. 6, 27519.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  16 Citations (Scopus)

• Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching

  Le, M. X., Haddad, D., Ling, A. K., Li, C., So, C. C., Chopra, A., Hu, R., Angulo, J. F., Moffat, J. & Martin, A., 17 Nov 2016, In: Scientific Reports. 6, 37215.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Lack of the programmed death-1 receptor renders host susceptible to enteric microbial infection through impairing the production of the mucosal natural killer cell effector molecules

  Solaymani-Mohammadi, S., Lakhdari, O., Minev, I., Shenouda, S., Frey, B. F., Billeskov, R., Singer, S. M., Berzofsky, J. A., Eckmann, L. & Kagnoff, M. F., 1 Mar 2016, In: Journal of Leukocyte Biology. 99, 3, p. 475-482 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Leveraging Health Information Technology for Fall-Risk Management in Home Care: A Qualitative Exploration of Clinicians’ Perspectives

  Alhuwail, D. & Koru, G., 1 Nov 2016, In: Home Health Care Management and Practice. 28, 4, p. 241-249 9 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Low serum vitamin-D status is associated with high prevalence and early onset of type-1 diabetes mellitus in Kuwaiti children

  Rasoul, M. A., Al-Mahdi, M., Mohammad Abdullah Al-kandari, H., Dhaunsi, G. S. & Haider, M. Z., 16 Jul 2016, In: BMC Pediatrics. 16, 1, 95.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Citations (Scopus)

• MAGI Proteins regulate the trafficking and signaling of corticotropin-releasing factor receptor 1 via a compensatory mechanism

  Hammad, M., Dunn, H. A. & Ferguson, S. S. G., 1 Jan 2016, In: Journal of Molecular Signaling. 11

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Normal Reference Ranges for Cardiac Valve Annulus in Preterm Infants

  Abushaban, L., Vel, M. T., Rathinasamy, J. & Sharma, P., 1 Jan 2016, In: Pediatric Cardiology. 37, 1, p. 112-119 8 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Nurse Informaticians Report Low Satisfaction and Multi-level Concerns with Electronic Health Records: Results from an International Survey

  Topaz, M., Ronquillo, C., Peltonen, L. M., Pruinelli, L., Sarmiento, R. F., Badger, M. K., Ali, S., Lewis, A., Georgsson, M., Jeon, E., Tayaben, J. L., Kuo, C. H., Islam, T., Sommer, J., Jung, H., Eler, G. J., Alhuwail, D. & Lee, Y. L., 1 Jan 2016, In: AMIA ... Annual Symposium proceedings. AMIA Symposium. 2016, p. 2016-2025 10 p.

  Research output: Contribution to journal › Article › peer-review

  29 Citations (Scopus)

• Nursing informatics research priorities for the future: Recommendations from an international survey

  Peltonen, L. M., Topaz, M., Ronquillo, C., Pruinelli, L., Sarmiento, R. F., Badger, M. K., Ali, S., Lewis, A., Georgsson, M., Jeon, E., Tayaben, J. L., Kuo, C. H., Islam, T., Sommer, J., Jung, H., Eler, G. J. & Alhuwail, D., 1 Jan 2016, Nursing Informatics 2016 - eHealth for All: Every Level Collaboration - From Project to Realization. Sermeus, W., Weber, P. & Procter, P. M. (eds.). p. 222-226 5 p. (Studies in Health Technology and Informatics; vol. 225).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
  7 Citations (Scopus)

• Older people’s priorities in health and social care research and practice: a public engagement workshop

  Alsaeed, D., Davies, N., Gilmartin, J. F. M., Jamieson, E., Kharicha, K., Liljas, A. E. M., Raimi-Abraham, B., Aldridge, J., Smith, F. J., Walters, K. & Gul, M. O., 2016, In: Research Involvement and Engagement.

  Research output: Contribution to journal › Article › peer-review

  7 Citations (Scopus)

• Overcoming Resistance to Endocrine Therapy in Breast Cancer: New Approaches to a Nagging Problem

  Luqmani, Y. A. & Alam-Eldin, N., 1 Jul 2016, In: Medical Principles and Practice. 25, 2, p. 28-40 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Citations (Scopus)

• Palmitate-Induced MMP-9 Expression in the Human Monocytic Cells is Mediated through the TLR4-MyD88 Dependent Mechanism

  Sindhu, S., Abu-AlRoub, A., Koshy, M., Thomas, R. & Ahmad, R., 1 Sep 2016, In: Cellular Physiology and Biochemistry. 39, 3, p. 889-900 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  41 Citations (Scopus)

• Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperone

  Khadir, A., Kavalakatt, S., Abubaker, J., Cherian, P., Madhu, D., Al khairi, I., Abu-Farha, M., Warsame, S., Elkum, N., Dehbi, M. & Tiss, A., 1 Sep 2016, In: Metabolism: Clinical and Experimental. 65, 9, p. 1409-1420 12 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• Plasma fetuin-A/α2-HS-glycoprotein correlates negatively with inflammatory cytokines, chemokines and activation biomarkers in individuals with type-2 diabetes

  Sindhu, S., Akhter, N., Shenouda, S., Wilson, A. & Ahmad, R., 26 Sep 2016, In: BMC Immunology. 17, 1, 33.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Citations (Scopus)

• Porcine islet-specific tolerance induced by the combination of anti-LFA-1 and anti-CD154 mabs is dependent on PD-1

  Arefanian, H., Tredget, E. B., Mok, D. C. M., Ramji, Q., Rafati, S., Rodriguez-Barbosa, J., Korbutt, G. S., Rajotte, R. V., Gill, R. G. & Rayat, G. R., 1 Jan 2016, In: Cell Transplantation. 25, 2, p. 327-342 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Prediabetes and risk of diabetes and associated complications: Impaired fasting glucose versus impaired glucose tolerance: does it matter?

  Abdulghani, M., Defronzo, R. A. & Jayyousi, A., 1 Sep 2016, In: Current Opinion in Clinical Nutrition and Metabolic Care. 19, 5, p. 394-399 6 p.

  Research output: Contribution to journal › Review article › peer-review
  24 Citations (Scopus)

• Prevalence of prediabetes and its association with obesity among college students in Kuwait: A cross-sectional study

  Ben Haider, N. Y. & H M Ziyab, A., 1 Sep 2016, In: Diabetes Research and Clinical Practice. 119, p. 71-74 4 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Prevalence of Urinary Tract Infection and Antimicrobial Susceptibility among Diabetic Patients with Controlled and Uncontrolled Glycemia in Kuwait

  Sewify, M., Nair, S., Warsame, S., Murad, M., Alhubail, A., Behbehani, K., Al-Refaei, F. & Tiss, A., 1 Jan 2016, In: Journal of Diabetes Research. 2016, 6573215.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  29 Citations (Scopus)

• Proliferation and Migration of Peripheral Retinal Pigment Epithelial Cells Are Associated with the Upregulation of Wingless-Related Integration and Bone Morphogenetic Protein Signaling in Dark Agouti Rats

  Al-Hussaini, H., Kilarkaje, N., Shahabi, G. & Al-Mulla, F., 1 Aug 2016, In: Medical Principles and Practice. 25, 5, p. 408-416 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)

• Referral pattern of children with short stature to a pediatric endocrine clinic in Kuwait

  Mahmoud Yousef Alabdulrazzaq, D., Al-Taiar, A., Hassan, K., Al-Twari, B., Al-Osaimi, A. & Al-Busairi, I., 1 Sep 2016, In: Journal of Pediatric Endocrinology and Metabolism. 29, 9, p. 1055-1061 7 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Revitalization of pioglitazone: The optimum agent to be combined with a sodium-glucose co-transporter-2 inhibitor

  Defronzo, R. A., Chilton, R., Norton, L., Clarke, G., Ryder, R. E. J. & Abdulghani, M., 1 May 2016, In: Diabetes, Obesity and Metabolism. 18, 5, p. 454-462 9 p.

  Research output: Contribution to journal › Article › peer-review
  31 Citations (Scopus)

• SGLT2 inhibitors and cardiovascular risk: Lessons learned from the EMPA-REG Outcome study

  Abdulghani, M., Del Prato, S., Chilton, R. & De Fronzo, R. A., 1 May 2016, In: Diabetes care. 39, 5, p. 717-725 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  195 Citations (Scopus)

• Supporting the information domains of fall-risk management in home care via health information technology

  Alhuwail, D., Koru, G. & Mills, M. E., 1 Oct 2016, In: Home Health Care Services Quarterly. 35, 3-4, p. 155-171 17 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• The effect of dietary changes on distinct components of the metabolic syndrome in a young Sri Lankan population at high risk of CVD

  Guess, N., Wijesuriya, M., Vasantharajah, L., Gulliford, M., Viberti, G., Gnudi, L. & Karalliedde, J., 28 Aug 2016, In: British Journal of Nutrition. 116, 4, p. 719-727 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• The oral-systemic disease connection: a retrospective study

  Joseph, B. K., Kullman, L. & Sharma, P., 1 Nov 2016, In: Clinical Oral Investigations. 20, 8, p. 2267-2273 7 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• The Rise and the Fall of Betatrophin/ANGPTL8 as an Inducer of β -Cell Proliferation

  Abu-Farha, M., Al Madhoun, A. & Abubaker, J., 1 Jan 2016, In: Journal of Diabetes Research. 2016, 4860595.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  10 Citations (Scopus)

• The role of Gut Microbiota in the development of obesity and Diabetes

  Baothman, O. A., Zamzami, M. A., Taher, I., Abubaker, J. & Abu-Farha, M., 18 Jun 2016, In: Lipids in Health and Disease. 15, 1, 108.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  189 Citations (Scopus)

• The SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation

  Ramachandran, S., Haddad, D., Li, C., Le, M. X., Ling, A. K., So, C. C., Nepal, R. M., Gommerman, J. L., Yu, K., Ketela, T., Moffat, J. & Martin, A., 17 May 2016, In: Cell Reports. 15, 7, p. 1554-1565 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  47 Citations (Scopus)

• Total energy expenditure in obese kuwaiti primary school children assessed by the doubly-labeled water technique

  Davidsson, L., Al-Ghanim, J., Al-Ati, T., Al-Hamad, N., Al-Mutairi, A., Al-Olayan, L. & Preston, T., 1 Oct 2016, In: International Journal of Environmental Research and Public Health. 13, 10, 1007.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Uncommon TERT promoter mutations in pediatric thyroid cancer

  Alzahrani, A. S., Qasem, E., Murugan, A. K., Al-Hindi, H. N., Alkhafaji, D., Almohanna, M., Xing, M., Saqer Hamad Alhmaidah, D. & Alswailem, M., 1 Feb 2016, In: Thyroid. 26, 2, p. 235-241 7 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Unraveling Kuwait-specific metabolic gene regulatory and coding variants: a step towards building a national exome database

  Nizam, R., Antony, DI., John, S. E., Hebbar, P., Melhem, M., Tuomilehto, J., Thanaraj, A. T. & Alsmadi, O., Dec 2016, WCPD9 Abstracts. Endocr Pract, Vol. 22 (suppl 6). p. 1-29

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review