Find Research Outputs — Dasman Diabetes Institute Research Portal

2014

Differential expression of alternative splice variants of CTLA4 in Kuwaiti autoimmune disease patients

AlFadhli, S. & Nizam, R., 25 Jan 2014, In : Gene. 534, 2, p. 307-312 6 p.

Research output: Contribution to journal › Article

Effect of vildagliptin add-on treatment to metformin on plasma asymmetric dimethylarginine in type 2 diabetes mellitus patients

Cakirca, M., Karatoprak, C., Zorlu, M., Kiskac, M., Kanat, M., Cikrikcioglu, M. A., Soysal, P., Hursitoglu, M., Camli, A. A., Erkoc, R. & Abdulghani, M., 14 Feb 2014, In : Drug Design, Development and Therapy. 8, p. 239-243 5 p.

Research output: Contribution to journal › Article

Open Access

8 Citations (Scopus)

Electronic Sample Management Portal - National Dasman Diabetes Biobank at Dasman Diabetes Institute, Kuwait

Sriraman, D., Shyamsundar, A., Koshy, M., Lopez, V., Mathur, A., Chandy, B., Kochumon, S., Thomas, R., Ali, A. & Moorji, A. K., 2014.

Research output: Contribution to conference › Poster

Erratum: Genome at juncture of early human migration: A systematic analysis of two whole genomes and thirteen exomes from kuwaiti population subgroup of inferred saudi arabian tribe ancestry (PLoS ONE (2014) 9, 6 (e99069) DOI: 10.1371/journal.pone.0099069)

Alsmadi, O., John, S. E., Thareja, G., Hebbar, P. & Antony, D., 21 Jul 2014, In : PloS one. 9, 7, e103691.

Research output: Contribution to journal › Comment/debate

Open Access

2 Citations (Scopus)

Erratum: Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production (Journal of Clinical Investigation (2014) 124:2 (509-514) DOI:10.1172/JCI70704)

Merovci, A., Solis-Herrera, C., Daniele, G., Eldor, R., Fiorentino, T. V., Tripathy, D., Xiong, J., Perez, Z., Norton, L., Abdulghani, M. & DeFronzo, R. A., 1 Jan 2014, In : Journal of Clinical Investigation. 124, 5, 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

1 Citation (Scopus)

Erratum to: Is Social Deprivation Associated with Weight Loss Outcomes Following Bariatric Surgery? A 10-Year Single Institutional Experience [OBES SURG, DOI 10.1007/s11695-014-1290-2]

Alfa Wali, M., Ashrafian, H., Schofield, K. L., Harling, L., Alkandari, A., Darzi, A., Athanasiou, T. & Efthimiou, E., 1 Jan 2014, In : Obesity Surgery. 24, 12, 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

FSL-1 induces MMP-9 production through TLR-2 and NF-κB /AP-1 signaling pathways in monocytic THP-1 cells

Ahmad, R., Kchumon, S., Jasem, S. & Behbehani, K., 12 Apr 2014, In : Cellular Physiology and Biochemistry. 34, 3, p. 929-942 14 p.

Research output: Contribution to journal › Article

Open Access

37 Citations (Scopus)

Gender-associated genomic differences in colorectal cancer: Clinical insight from feminization of male cancer cells

Ali, R. H., Marafie, M. J., Sami Bitar, M., Al-Dousari, F., Ismael, S., Haider, H. B., Al-Ali, W., Al-Mulla, F. & Jacob, S., 29 Sep 2014, In : International Journal of Molecular Sciences. 15, 10, p. 17344-17365 22 p.

Research output: Contribution to journal › Article

Open Access

10 Citations (Scopus)

Gender differences in ghrelin association with cardiometabolic risk factors in arab population

Abu-Farha, M., Dehbi, M., Noronha, F., Tiss, A., Alarouj, M., Behbehani, K., Bennakhi, A. & Elkum, N., 1 Jan 2014, In : International Journal of Endocrinology. 2014, 730472.

Research output: Contribution to journal › Article

Open Access

10 Citations (Scopus)

Genetic and epigenetic control of RKIP transcription

Datar, I., Tegegne, H., Qin, K., Al-Mulla, F., Sami Bitar, M., Trumbly, R. J. & Yeung, K. C., 1 Jan 2014, In : Critical Reviews in Oncogenesis. 19, 6, p. 417-430 14 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Genome at juncture of early human migration: A systematic analysis of two whole genomes and thirteen exomes from Kuwaiti population subgroup of inferred Saudi Arabian tribe ancestry

Alsmadi, O., John, S. E., Thareja, G., Hebbar, P., Antony, D., Behbehani, K. & Thanaraj, A. T., 4 Jun 2014, In : PloS one. 9, 6, e99069.

Research output: Contribution to journal › Article

Open Access

20 Citations (Scopus)

Genomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development

Shalhout, S., Haddad, D., Sosin, A., Holland, T. C., Al-Katib, A., Martin, A. & Bhagwata, A. S., 1 Jan 2014, In : Molecular and Cellular Biology. 34, 21, p. 4019-4032 14 p.

Research output: Contribution to journal › Article

Open Access

13 Citations (Scopus)

Helicobacter pylori infection in pregnant women in four districts of Uganda: Role of geographic location, education and water sources

Baingana, R. K., Kiboko Enyaru, J. & Davidsson, L., 4 Sep 2014, In : BMC Public Health. 14, 1, 915.

Research output: Contribution to journal › Article

Open Access

19 Citations (Scopus)

IL-33 is negatively associated with the BMI and confers a protective lipid/metabolic profile in non-diabetic but not diabetic subjects

Hasan, A., Al-Ghimlas, F., Warsame, S., Al-Hubail, A., Ahmad, R., Bennakhi, A., Al-Arouj, M., Behbehani, K., Dehbi, M. & Dermime, S., 10 May 2014, In : BMC Immunology. 15, 1, 19.

Research output: Contribution to journal › Article

Open Access

28 Citations (Scopus)

Immunogenetics of type 1 diabetes and its associated complications

Jahromi, M., 1 Jan 2014, Type 1 Diabetes: Causes, Treatment and Potential Complications. p. 69-101 33 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue

Tiss, A., Khadir, A., Abubaker, J., Abu-Farha, M., Al khairi, I., Cherian, P., John, J., Kavalakatt, S., Warsame, S., Al-Ghimlas, F., Elkum, N., Behbehani, K., Dermime, S. & Dehbi, M., 1 Jul 2014, In : Lipids in Health and Disease. 13, 1, 106.

Research output: Contribution to journal › Article

Open Access

25 Citations (Scopus)

Impact of hypertension on the association of BMI with risk and age at onset of type 2 diabetes mellitus: Ageand gender-mediated modifications

Channanath, A., Farran, B., Behbehani, K. & Thanaraj, A. T., 17 Apr 2014, In : PloS one. 9, 4, e95308.

Research output: Contribution to journal › Article

Open Access

8 Citations (Scopus)

Implementing Family Health History Approach as a Potential Screening Tool for Disease Risk Prediction in Genetic Studies

Mahmoud Kamkar, M., Alsmadi, O., Sriraman, D. & Thomas, D., 20 Feb 2014.

Research output: Contribution to conference › Poster

Innovative tools for early detection of cancer

Tiss, A., Hasan, A., Khadir, A., Dehbi, M. & Dermime, S., 1 Jan 2014, Cancer Biomarkers: Minimal and Noninvasive Early Diagnosis and Prognosis. p. 47-84 38 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Insight into the impact of diabetes mellitus on the increased risk of hepatocellular carcinoma: Mini-review

Mahmoud Ali, M., Ahmad, R., Alsmadi, O. & Behbehani, K., 22 May 2014, In : Journal of Diabetes and Metabolic Disorders. 13, 1, 57.

Research output: Contribution to journal › Review article

Open Access

10 Citations (Scopus)

Intramyocellular lipid dependence on skeletal muscle fiber type and orientation characterized by diffusion tensor imaging and ¹H-MRS

Valaparla, S. K., Gao, F., Abdulghani, M. & Clarke, G. D., 1 Jan 2014, Medical Imaging 2014: Image Processing. 90340S. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9034).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Is Social Deprivation Associated with Weight Loss Outcomes Following Bariatric Surgery? A 10-Year Single Institutional Experience

Alfa Wali, M., Ashrafian, H., Schofield, K. L., Harling, L., Alkandari, A., Darzi, A., Athansiou, T. & Efthimiou, E., 1 Jan 2014, In : Obesity Surgery. 24, 12, p. 2126-2132 7 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Leptin in association with common variants of MC3R mediates hypertension

Alsmadi, O., Melhem, M., Hebbar, P., Thareja, G., John, S. E., Alkayal, F., Behbehani, K. & Thanaraj, A. T., 1 Jan 2014, In : American Journal of Hypertension. 27, 7, p. 973-981 9 p.

Research output: Contribution to journal › Article

Open Access

11 Citations (Scopus)

Lowering plasma glucose concentration by inhibiting renal sodium-glucose cotransport

Abdulghani, M. & Defronzo, R. A., 1 Oct 2014, In : Journal of Internal Medicine. 276, 4, p. 352-363 12 p.

Research output: Contribution to journal › Review article

Open Access

34 Citations (Scopus)

Molecular characterization of a population-based series of endometrial stromal sarcomas in Kuwait

Ali, R. H., Al-Safi, R., Al-Waheeb, S., John, B., Al-Ali, W., Al-Jassar, W., Al-Mulla, F., Melnyk, N., Huntsman, D. G. & Lee, C. H., 1 Dec 2014, In : Human Pathology. 45, 12, p. 2453-2462 10 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

ND4L gene concurrent 10609T>C and 10663T>C mutations are associated with Leber's hereditary optic neuropathy in a large pedigree from Kuwait

Behbehani, R., Melhem, M., Alghanim, G., Behbehani, K. & Alsmadi, O., 1 Jan 2014, In : British Journal of Ophthalmology. 98, 6, p. 826-831 6 p.

Research output: Contribution to journal › Article

Open Access

6 Citations (Scopus)

Normal reference ranges for left ventricular dimensions in preterm infants

Abushaban, L., Vel, M. T., Rathinasamy, J. & Sharma, P., 1 Sep 2014, In : Annals of Pediatric Cardiology. 7, 3, p. 180-186 7 p.

Research output: Contribution to journal › Article

Open Access

10 Citations (Scopus)

Novel agents for the treatment of type 2 diabetes

DeFronzo, R. A., Triplitt, C. L., Abdulghani, M. & Cersosimo, E., 1 Jan 2014, In : Diabetes Spectrum. 27, 2, p. 100-112 13 p.

Research output: Contribution to journal › Review article

Open Access

26 Citations (Scopus)

Oral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylation

Guthikonda, K., Zhang, H., Nolan, V. G., Soto-Ramírez, N., H M Ziyab, A., Ewart, S., Arshad, H. S., Patil, V., Holloway, J. W., Lockett, G. A. & Karmaus, W., 19 Sep 2014, In : Clinical Epigenetics. 6, 1, 17.

Research output: Contribution to journal › Article

Open Access

15 Citations (Scopus)

Overexpression of the cancer-related DUSP1 gene in human obesity and its modulation by physical exercise

Khadir, A., Tiss, A., Abubaker, J., Abu-farha, M., Dermime, S. & Dehbi, M., 2014, In : Journal for ImmunoTherapy of Cancer. 2, Suppl 1, p. P5—P5

Research output: Contribution to journal › Article

Physical exercise reduces the expression of RANTES and its CCR5 receptor in the adipose tissue of obese humans

Baturcam, E., Abubaker, J., Tiss, A., Abu-Farha, M., Khadir, A., Al-Ghimlas, F., Al khairi, I., Cherian, P., Elkum, N., Hammad, M., John, J., Kavalakatt, S., Lehe, C., Warsame, S., Behbehani, K., Dermime, S. & Dehbi, M., 1 Jan 2014, In : Mediators of Inflammation. 2014, 627150.

Research output: Contribution to journal › Article

Open Access

23 Citations (Scopus)

Raf Kinase Inhibitor Protein (RKIP) blocks Signal Transducer and Activator of Transcription 3 (STAT3) activation in breast and prostate cancer

Yousuf, S., Duan, M. L., Moen, E. L., Cross-Knorr, S., Brilliant, K., Bonavida, B., LaValle, T., Yeung, K. C., Al-Mulla, F., Chin, E. & Chatterjee, D., 21 Mar 2014, In : PloS one. 9, 3, e92478.

Research output: Contribution to journal › Article

Open Access

35 Citations (Scopus)

Raf kinase inhibitory protein role in the molecular subtyping of breast cancer

Al-Mulla, F., Marafie, M., Tan, T. Z. & Thiery, J. P., 1 Jan 2014, In : Journal of Cellular Biochemistry. 115, 3, p. 488-497 10 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

Regulation of the MAPK pathway by Raf kinase inhibitory protein

Vandamme, D., Herrero, A., Al-Mulla, F. & Kolch, W., 1 Jan 2014, In : Critical Reviews in Oncogenesis. 19, 6, p. 405-415 11 p.

Research output: Contribution to journal › Article

15 Citations (Scopus)

Relationship between patient satisfactions with diabetes care and treatment

Bener, A., Al-Hamaq, A. O., Yousafzai, M. T. & Abdulghani, M., 1 Mar 2014, In : Nigerian Journal of Clinical Practice. 17, 2, p. 218-225 8 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Response to leptin and nitric oxide in blood pressure regulation in humans

Alsmadi, O., Melhem, M., Hebbar, P., Channanath, A., Thareja, G., John, S. E., Alkayal, F., Behbehani, K. & Thanaraj, A. T., 27 Jul 2014, In : American Journal of Hypertension. 27, 11, p. 1429-1430 2 p.

Research output: Contribution to journal › Letter

Open Access

3 Citations (Scopus)

Rhupus: A crosswalk between lupus and rheumatoid arthritis.

Alfadhli, S. & Nizam, R., 10 Feb 2014, In : OA Arthritis. 10;2(1):3., p. 2(1):3.

Research output: Contribution to journal › Review article

Senior-Loken syndrome: A novel NPHP5 gene mutation in a family from Kuwait

Marafie, M. J. & Al-Mulla, F., 1 Apr 2014, In : Egyptian Journal of Medical Human Genetics. 15, 2, p. 203-207 5 p.

Research output: Contribution to journal › Article

Open Access

1 Citation (Scopus)

Strong association between insulin-mediated glucose uptake and the 2-hour, not the fasting plasma glucose concentration, in the normal glucose tolerance range

Winnier, D., Norton, L., Kanat, M., Arya, R., Fourcaudot, M., Hansis-Diarte, A., Tripathy, D., De Fronzo, R. A., Jenkinson, C. P. & Abdulghani, M., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. 3444-3449 6 p.

Research output: Contribution to journal › Article

Open Access

8 Citations (Scopus)

Sudden cardiac death diagnosed with dilated cardiomyopathy in a Kuwaiti family: A case report

Bulbanat, B., Antony, D., Behbehani, K., Alsmadi, O., Thomas, D. & Mahmoud Kamkar, M., 1 Jan 2014, In : BMC Research Notes. 7, 1, 904.

Research output: Contribution to journal › Article

Open Access

1 Citation (Scopus)

The disposition index does not reflect β-cell function in IGT subjects treated with pioglitazone

Defronzo, R. A., Tripathy, D., Abdulghani, M., Musi, N. & Gastaldelli, A., 1 Oct 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 10, p. 3774-3781 8 p.

Research output: Contribution to journal › Article

Open Access

15 Citations (Scopus)

The effect of feto-maternal blood type incompatibility on development of gestational diabetes mellitus

Kanat, M., Goksugur, S. B., Ozlu, T., Tunckale, A., Ozturk, B., Ozturk, F. Y., Altuntas, Y., Suleymanoglu, Y., Atmaca, H., Yolcu, N., Gonenc, I., Delibasi, T., Zuhur, S., Dikbas, O., Aktas, G., Karagoz, Y. & Abdulghani, M., 1 Jan 2014, In : Clinica Terapeutica. 165, 2

Research output: Contribution to journal › Article

3 Citations (Scopus)

The influence of admixture and consanguinity on population genetic diversity in Middle East

Yang, X., Al-Bustan, S., Feng, Q., Guo, W., Ma, Z., Marafie, M., Jacob, S., Al-Mulla, F. & Xu, S., 11 Nov 2014, In : Journal of Human Genetics. 59, 11, p. 615-622 8 p.

Research output: Contribution to journal › Article

8 Citations (Scopus)

The locked genomes: A perspective from Arabia

Al-Mulla, F., 1 Dec 2014, In : Applied and Translational Genomics. 3, 4, p. 132-133 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

6 Citations (Scopus)

The population genomic landscape of human genetic structure, admixture history and local adaptation in Peninsular Malaysia

Deng, L., Hoh, B. P., Lu, D., Fu, R., Phipps, M. E., Li, S., Nur-Shafawati, A. R., Hatin, W. I., Ismail, E., Mokhtar, S. S., Jin, L., Zilfalil, B. A., Marshall, C. R., Scherer, S. W., Al-Mulla, F. & Xu, S., 1 Sep 2014, In : Human Genetics. 133, 9, p. 1169-1185 17 p.

Research output: Contribution to journal › Article

16 Citations (Scopus)

Open Access

41 Citations (Scopus)

What are the pharmacotherapy options for treating prediabetes?

Daniele, G., Abdulghani, M. & Defronzo, R. A., 1 Oct 2014, In : Expert Opinion on Pharmacotherapy. 15, 14, p. 2003-2018 16 p.

Research output: Contribution to journal › Review article

11 Citations (Scopus)

2013

AID and caspase 8 shape the germinal center response through apoptosis

Boulianne, B., Rojas, O. L., Haddad, D., Zaheen, A., Kapelnikov, A., Nguyen, T., Li, C., Hakem, R., Gommerman, J. L. & Martin, A., 15 Dec 2013, In : Journal of Immunology. 191, 12, p. 5840-5847 8 p.

Research output: Contribution to journal › Article

Open Access

7 Citations (Scopus)