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2014

Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue

Tiss, A., Khadir, A., Abubaker, J., Abu-Farha, M., Al khairi, I., Cherian, P., John, J., Kavalakatt, S., Warsame, S., Al-Ghimlas, F., Elkum, N., Behbehani, K., Dermime, S. & Dehbi, M., 1 Jul 2014, In : Lipids in Health and Disease. 13, 1, 106.

Research output: Contribution to journal › Article

Open Access
26 Citations (Scopus)

Impact of hypertension on the association of BMI with risk and age at onset of type 2 diabetes mellitus: Ageand gender-mediated modifications

Channanath, A., Farran, B., Behbehani, K. & Thanaraj, A. T., 17 Apr 2014, In : PloS one. 9, 4, e95308.

Research output: Contribution to journal › Article

Open Access
8 Citations (Scopus)

Implementing Family Health History Approach as a Potential Screening Tool for Disease Risk Prediction in Genetic Studies

Mahmoud Kamkar, M., Alsmadi, O., Sriraman, D. & Thomas, D., 20 Feb 2014.

Research output: Contribution to conference › Poster

Innovative tools for early detection of cancer

Tiss, A., Hasan, A., Khadir, A., Dehbi, M. & Dermime, S., 1 Jan 2014, Cancer Biomarkers: Minimal and Noninvasive Early Diagnosis and Prognosis. p. 47-84 38 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Insight into the impact of diabetes mellitus on the increased risk of hepatocellular carcinoma: Mini-review

Mahmoud Ali, M., Ahmad, R., Alsmadi, O. & Behbehani, K., 22 May 2014, In : Journal of Diabetes and Metabolic Disorders. 13, 1, 57.

Research output: Contribution to journal › Review article

Open Access
11 Citations (Scopus)

Intramyocellular lipid dependence on skeletal muscle fiber type and orientation characterized by diffusion tensor imaging and 1H-MRS

Valaparla, S. K., Gao, F., Abdulghani, M. & Clarke, G. D., 1 Jan 2014, Medical Imaging 2014: Image Processing. 90340S. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9034).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Is Social Deprivation Associated with Weight Loss Outcomes Following Bariatric Surgery? A 10-Year Single Institutional Experience

Alfa Wali, M., Ashrafian, H., Schofield, K. L., Harling, L., Alkandari, A., Darzi, A., Athansiou, T. & Efthimiou, E., 1 Jan 2014, In : Obesity Surgery. 24, 12, p. 2126-2132 7 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

Leptin in association with common variants of MC3R mediates hypertension

Alsmadi, O., Melhem, M., Hebbar, P., Thareja, G., John, S. E., Alkayal, F., Behbehani, K. & Thanaraj, A. T., 1 Jan 2014, In : American Journal of Hypertension. 27, 7, p. 973-981 9 p.

Research output: Contribution to journal › Article

Open Access
11 Citations (Scopus)

Lowering plasma glucose concentration by inhibiting renal sodium-glucose cotransport

Abdulghani, M. & Defronzo, R. A., 1 Oct 2014, In : Journal of Internal Medicine. 276, 4, p. 352-363 12 p.

Research output: Contribution to journal › Review article

Open Access
34 Citations (Scopus)

Molecular characterization of a population-based series of endometrial stromal sarcomas in Kuwait

Ali, R. H., Al-Safi, R., Al-Waheeb, S., John, B., Al-Ali, W., Al-Jassar, W., Al-Mulla, F., Melnyk, N., Huntsman, D. G. & Lee, C. H., 1 Dec 2014, In : Human Pathology. 45, 12, p. 2453-2462 10 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

ND4L gene concurrent 10609T>C and 10663T>C mutations are associated with Leber's hereditary optic neuropathy in a large pedigree from Kuwait

Behbehani, R., Melhem, M., Alghanim, G., Behbehani, K. & Alsmadi, O., 1 Jan 2014, In : British Journal of Ophthalmology. 98, 6, p. 826-831 6 p.

Research output: Contribution to journal › Article

Open Access
6 Citations (Scopus)

Normal reference ranges for left ventricular dimensions in preterm infants

Abushaban, L., Vel, M. T., Rathinasamy, J. & Sharma, P., 1 Sep 2014, In : Annals of Pediatric Cardiology. 7, 3, p. 180-186 7 p.

Research output: Contribution to journal › Article

Open Access
10 Citations (Scopus)

Novel agents for the treatment of type 2 diabetes

DeFronzo, R. A., Triplitt, C. L., Abdulghani, M. & Cersosimo, E., 1 Jan 2014, In : Diabetes Spectrum. 27, 2, p. 100-112 13 p.

Research output: Contribution to journal › Review article

Open Access
29 Citations (Scopus)

Oral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylation

Guthikonda, K., Zhang, H., Nolan, V. G., Soto-Ramírez, N., H M Ziyab, A., Ewart, S., Arshad, H. S., Patil, V., Holloway, J. W., Lockett, G. A. & Karmaus, W., 19 Sep 2014, In : Clinical Epigenetics. 6, 1, 17.

Research output: Contribution to journal › Article

Open Access
16 Citations (Scopus)

Overexpression of the cancer-related DUSP1 gene in human obesity and its modulation by physical exercise

Khadir, A., Tiss, A., Abubaker, J., Abu-farha, M., Dermime, S. & Dehbi, M., 2014, In : Journal for ImmunoTherapy of Cancer. 2, Suppl 1, p. P5—P5

Research output: Contribution to journal › Article

Physical exercise reduces the expression of RANTES and its CCR5 receptor in the adipose tissue of obese humans

Baturcam, E., Abubaker, J., Tiss, A., Abu-Farha, M., Khadir, A., Al-Ghimlas, F., Al khairi, I., Cherian, P., Elkum, N., Hammad, M., John, J., Kavalakatt, S., Lehe, C., Warsame, S., Behbehani, K., Dermime, S. & Dehbi, M., 1 Jan 2014, In : Mediators of Inflammation. 2014, 627150.

Research output: Contribution to journal › Article

Open Access
24 Citations (Scopus)

Raf Kinase Inhibitor Protein (RKIP) blocks Signal Transducer and Activator of Transcription 3 (STAT3) activation in breast and prostate cancer

Yousuf, S., Duan, M. L., Moen, E. L., Cross-Knorr, S., Brilliant, K., Bonavida, B., LaValle, T., Yeung, K. C., Al-Mulla, F., Chin, E. & Chatterjee, D., 21 Mar 2014, In : PloS one. 9, 3, e92478.

Research output: Contribution to journal › Article

Open Access
36 Citations (Scopus)

Raf kinase inhibitory protein role in the molecular subtyping of breast cancer

Al-Mulla, F., Marafie, M., Tan, T. Z. & Thiery, J. P., 1 Jan 2014, In : Journal of Cellular Biochemistry. 115, 3, p. 488-497 10 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

Regulation of the MAPK pathway by Raf kinase inhibitory protein

Vandamme, D., Herrero, A., Al-Mulla, F. & Kolch, W., 1 Jan 2014, In : Critical Reviews in Oncogenesis. 19, 6, p. 405-415 11 p.

Research output: Contribution to journal › Article

15 Citations (Scopus)

Relationship between patient satisfactions with diabetes care and treatment

Bener, A., Al-Hamaq, A. O., Yousafzai, M. T. & Abdulghani, M., 1 Mar 2014, In : Nigerian Journal of Clinical Practice. 17, 2, p. 218-225 8 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Response to leptin and nitric oxide in blood pressure regulation in humans

Alsmadi, O., Melhem, M., Hebbar, P., Channanath, A., Thareja, G., John, S. E., Alkayal, F., Behbehani, K. & Thanaraj, A. T., 27 Jul 2014, In : American Journal of Hypertension. 27, 11, p. 1429-1430 2 p.

Research output: Contribution to journal › Letter

Open Access
3 Citations (Scopus)

Rhupus: A crosswalk between lupus and rheumatoid arthritis.

Alfadhli, S. & Nizam, R., 10 Feb 2014, In : OA Arthritis. 10;2(1):3., p. 2(1):3.

Research output: Contribution to journal › Review article

Senior-Loken syndrome: A novel NPHP5 gene mutation in a family from Kuwait

Marafie, M. J. & Al-Mulla, F., 1 Apr 2014, In : Egyptian Journal of Medical Human Genetics. 15, 2, p. 203-207 5 p.

Research output: Contribution to journal › Article

Open Access
1 Citation (Scopus)

Strong association between insulin-mediated glucose uptake and the 2-hour, not the fasting plasma glucose concentration, in the normal glucose tolerance range

Winnier, D., Norton, L., Kanat, M., Arya, R., Fourcaudot, M., Hansis-Diarte, A., Tripathy, D., De Fronzo, R. A., Jenkinson, C. P. & Abdulghani, M., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. 3444-3449 6 p.

Research output: Contribution to journal › Article

Open Access
8 Citations (Scopus)

Sudden cardiac death diagnosed with dilated cardiomyopathy in a Kuwaiti family: A case report

Bulbanat, B., Antony, D., Behbehani, K., Alsmadi, O., Thomas, D. & Mahmoud Kamkar, M., 1 Jan 2014, In : BMC Research Notes. 7, 1, 904.

Research output: Contribution to journal › Article

Open Access
1 Citation (Scopus)

The disposition index does not reflect β-cell function in IGT subjects treated with pioglitazone

Defronzo, R. A., Tripathy, D., Abdulghani, M., Musi, N. & Gastaldelli, A., 1 Oct 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 10, p. 3774-3781 8 p.

Research output: Contribution to journal › Article

Open Access
17 Citations (Scopus)

The effect of feto-maternal blood type incompatibility on development of gestational diabetes mellitus

Kanat, M., Goksugur, S. B., Ozlu, T., Tunckale, A., Ozturk, B., Ozturk, F. Y., Altuntas, Y., Suleymanoglu, Y., Atmaca, H., Yolcu, N., Gonenc, I., Delibasi, T., Zuhur, S., Dikbas, O., Aktas, G., Karagoz, Y. & Abdulghani, M., 1 Jan 2014, In : Clinica Terapeutica. 165, 2

Research output: Contribution to journal › Article

3 Citations (Scopus)

The influence of admixture and consanguinity on population genetic diversity in Middle East

Yang, X., Al-Bustan, S., Feng, Q., Guo, W., Ma, Z., Marafie, M., Jacob, S., Al-Mulla, F. & Xu, S., 11 Nov 2014, In : Journal of Human Genetics. 59, 11, p. 615-622 8 p.

Research output: Contribution to journal › Article

8 Citations (Scopus)

The locked genomes: A perspective from Arabia

Al-Mulla, F., 1 Dec 2014, In : Applied and Translational Genomics. 3, 4, p. 132-133 2 p.

Research output: Contribution to journal › Comment/debate

Open Access
6 Citations (Scopus)

The population genomic landscape of human genetic structure, admixture history and local adaptation in Peninsular Malaysia

Deng, L., Hoh, B. P., Lu, D., Fu, R., Phipps, M. E., Li, S., Nur-Shafawati, A. R., Hatin, W. I., Ismail, E., Mokhtar, S. S., Jin, L., Zilfalil, B. A., Marshall, C. R., Scherer, S. W., Al-Mulla, F. & Xu, S., 1 Sep 2014, In : Human Genetics. 133, 9, p. 1169-1185 17 p.

Research output: Contribution to journal › Article

17 Citations (Scopus)

Tissue Bank Core Facility at Dasman Diabetes Institute Kuwait – An Overview

Sriraman, D., Shyamsundar, A., Thomas, R., Koshy, M., Lopez, V., Mathur, A., Chandy, B. S., Kochumon, S., Ali, A. & Moorji, A. K., 2014.

Research output: Contribution to conference › Poster

Treatment of prediabetes

Abdulghani, M., Kanat, M. & DeFronzo, R. A., 1 Jan 2014, Global Health Perspectives in Prediabetes and Diabetes Prevention. p. 75-108 34 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Vitamin D insufficiency in Arabs and South Asians positively associates with polymorphisms in GC and CYP2R1 genes

Elkum, N., Alkayal, F., Noronha, F., Mahmoud Kamkar, M., Melhem, M., Al-Arouj, M., Bennakhi, A., Behbehani, K., Alsmadi, O. & Abubaker, J., 18 Nov 2014, In : PloS one. 9, 11, e113102.

Research output: Contribution to journal › Article

Open Access
43 Citations (Scopus)

What are the pharmacotherapy options for treating prediabetes?

Daniele, G., Abdulghani, M. & Defronzo, R. A., 1 Oct 2014, In : Expert Opinion on Pharmacotherapy. 15, 14, p. 2003-2018 16 p.

Research output: Contribution to journal › Review article

11 Citations (Scopus)
2013

AID and caspase 8 shape the germinal center response through apoptosis

Boulianne, B., Rojas, O. L., Haddad, D., Zaheen, A., Kapelnikov, A., Nguyen, T., Li, C., Hakem, R., Gommerman, J. L. & Martin, A., 15 Dec 2013, In : Journal of Immunology. 191, 12, p. 5840-5847 8 p.

Research output: Contribution to journal › Article

Open Access
7 Citations (Scopus)

AID-expressing germinal center B cells cluster normally within lymph node follicles in the absence of FDC-M1+ CD35+ follicular dendritic cells but dissipate prematurely

Boulianne, B., Le, M. X., Ward, L. A., Meng, L., Haddad, D., Li, C., Martin, A. & Gommerman, J. L., 1 Nov 2013, In : Journal of Immunology. 191, 9, p. 4521-4530 10 p.

Research output: Contribution to journal › Article

Open Access
12 Citations (Scopus)

An antibiotic formulary for a tertiary care foot clinic: Admission avoidance using intramuscular antibiotics for borderline foot infections in people with diabetes

Gooday, C., Hallam, C., Sieber, C., Mtariswa, L., Turner, J., Schelenz, S., Murchison, R., Messenger, G., Morrow, D., Hutchinson, R., Williams, H. & Dhatariya, K., 1 May 2013, In : Diabetic Medicine. 30, 5, p. 581-589 9 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

An obesity agent based model: A new decision support system for the obesity epidemic

KH H Bourisly, A., 1 Jan 2013, AsiaSim 2013 - 13th International Conference on Systems Simulation, Proceedings. p. 37-48 12 p. (Communications in Computer and Information Science; vol. 402).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Avoiding honest feedback: Discordance between formal evaluations and candid assessments of Kuwaiti PBL students

Qadan, L., Al Ozairi, E., Ayed, A. & Huang, G., 1 Jun 2013, In : Medical Teacher. 35, 6, p. 459-464 6 p.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Body Composition Assessment from Birth to Two Years of Age: IAEA Human Health Series No. 22

Davidsson, L. (ed.) & Slater, C. (ed.), 2013, Body Composition Assessment from Birth to Two Years of Age: IAEA Human Health Series No. 22. Vienna, Austria

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Cardiovascular risk and atherosclerosis prevention

Frohlich, J. & AlSarraf, A., 1 Jan 2013, In : Cardiovascular Pathology. 22, 1, p. 16-18 3 p.

Research output: Contribution to journal › Review article

40 Citations (Scopus)

Caveolin-1/PTRF upregulation constitutes a mechanism for mediating p53-induced cellular senescence: Implications for evidence-based therapy of delayed wound healing in diabetes

Sami Bitar, M., Abdel-Halim, S. M. & Al-Mulla, F., 15 Oct 2013, In : American Journal of Physiology - Endocrinology and Metabolism. 305, 8

Research output: Contribution to journal › Article

31 Citations (Scopus)

Clinicopathological study of 25 cases of diverticular disease of the appendix: Experience from Farwaniya hospital

Al-Brahim, N., Al-Kandari, I., Munahai, M. & Sharma, P., 4 Nov 2013, In : Pathology Research International. 2013, 404308.

Research output: Contribution to journal › Article

Open Access
8 Citations (Scopus)

Dapagliflozin for the treatment of type 2 diabetes

Abdulghani, M. & Defronzo, R. A., 1 Aug 2013, In : Expert Opinion on Pharmacotherapy. 14, 12, p. 1695-1703 9 p.

Research output: Contribution to journal › Review article

14 Citations (Scopus)

Directed differentiation of umbilical cord blood stem cells into cortical GABAergic neurons

Mohamed Ali Yaseen, H., Bayatti, N., Lindsay, S., Dashti, A. A. & Al-Mulla, F., 9 Jul 2013, In : Acta Neurobiologiae Experimentalis. 73, 2, p. 250-259 10 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

Distribution of human papillomavirus among women with abnormal cervical cytology in Kuwait

Al-Awadhi, R., Chehadeh, W., Jaragh, M., Al-Shaheen, A., Sharma, P. & Kapila, K., 1 Feb 2013, In : Diagnostic Cytopathology. 41, 2, p. 107-114 8 p.

Research output: Contribution to journal › Article

23 Citations (Scopus)

DNAJB3/HSP-40 Cochaperone Is Downregulated in Obese Humans and Is Restored by Physical Exercise

Abubaker, J., Tiss, A., Abu-Farha, M., Al-Ghimlas, F., Al khairi, I., Baturcam, E., Cherian, P., Elkum, N., Hammad, M., John, J., Kavalakatt, S., Khadir, A., Warsame, S., Dermime, S., Behbehani, K. & Dehbi, M., 24 Jul 2013, In : PloS one. 8, 7, e69217.

Research output: Contribution to journal › Article

Open Access
31 Citations (Scopus)

DNAJB3/HSP-40 cochaperone role in obesity

Jehad, A., Abu-Farha, M., Al-Ghimlas, F., Alkhairi, I., Cherian, P., Elkum, N., John, J., Kavalakatt, S., Khadir, A. & Tiss, A., 2013, DIABETOLOGIA. Vol. 56. p. S314-S315

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants

H M Ziyab, A., Karmaus, W., Holloway, J. W., Zhang, H., Ewart, S. & Arshad, S. H., 1 Mar 2013, In : Journal of the European Academy of Dermatology and Venereology. 27, 3

Research output: Contribution to journal › Article

Open Access
36 Citations (Scopus)

Dynamic Changes in Oct4 Expression in Parallel With Human Islet Dedifferentiation / Redifferentiation in vitro

Aldibbiat, A. M., White, GM., Alturaifi, H., Marshall, H. & Shaw, J. A. M., 2013.

Research output: Contribution to conference › Poster