Bangladeshi rural mothers prepare safer rice oral rehydration solution

A. M. Molla, A. Bari, W. B. Greenough, A. M. Molla, P. Budhiraja, Prem Sharma

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Mothers in rural Bangladesh were trained to prepare and use either Rice-ORS (R-ORS) or Glucose-ORS (G-ORS) solutions to treat children with diarrhoea. Families were provided with either G-ORS or R-ORS of the same electrolyte composition through a depot holder. Subsequently, random samples of solutions actually used for treatment by the mothers were collected from homes by field workers. A total of 227 R-ORS and 239 G-ORS samples were analysed. The sodium concentration in about 90% of the samples had a safe range (50-120 mmol/l). Only 4% of R-ORS solutions were above 120 mmol/l in sodium concentration, while 12% of G-ORS solutions exceeded these limits (p < 0.0025). R-ORS (after acid hydrolysis) provided significantly higher glucose (257 ± 42 mmol/l) for active but safe absorption compared to G-ORS (115 ± 39 mmol/l). To make R-ORS liquid enough to drink requires addition of sufficient water, preventing the risk of higher sodium concentration. Unlike rice starch, glucose is a highly soluble substance. It is thus possible to prepare a drinkable solution containing dangerously high concentrations of both sodium and glucose, but this can be minimized by more intensive training of the mothers.

Original languageEnglish
Pages (from-to)791-794
Number of pages4
JournalActa Paediatrica, International Journal of Paediatrics
Volume89
Issue number7
DOIs
Publication statusPublished - 1 Jan 2000

    Fingerprint

Keywords

  • Biochemical analysis
  • Glucose ORS
  • Hydrolysis
  • Rice ORS
  • Safety

Cite this