Manganese absorption from mangold (Beta vulgaris): comparison of intrinsic and extrinsic labels

Lena Davidsson; Ake Cederblad; Bo Lönnerdal; Brittmarie Sandström

doi:10.1016/0955-2863(91)90075-G

Manganese absorption from mangold (Beta vulgaris): comparison of intrinsic and extrinsic labels

Lena Davidsson, Ake Cederblad, Bo Lönnerdal, Brittmarie Sandström

Population Health

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The validity of the use of extrinsic labeling for studies of manganese absorption in man was evaluated using a test meal containing Beta vulgaris intrinsically labeled with ⁵⁴Mn to which ⁵²Mn was added extrinsically. Whole body retention of the two isotopes was measured in a whole body counter during days 7-25 after administration of the test meal to six subjects. No difference in level of retention or rate of excretion was observed for the two isotopes. The calculated absorption (X = SD) was 6.0 ± 3.4% and 6.2 ± 2.9% for ⁵⁴Mn and ⁵²Mn, respectively, resulting in a ⁵⁴Mn : ⁵²Mn ratio for fractional absorption from the test meal of 0.95 ± 0.14 (X ± SD). These results demonstrate that extrinsic labeling with radioisotopes of manganese is a valid method for measurement of manganese absorption from vegetables when studied in humans.

Original language	English
Pages (from-to)	323-326
Number of pages	4
Journal	The Journal of Nutritional Biochemistry
Volume	2
Issue number	6
DOIs	https://doi.org/10.1016/0955-2863(91)90075-G
Publication status	Published - 1 Jan 1991

Keywords

Mn
Mn
extrinsic label
intrinsic label
manganese
whole body counting

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title = "Manganese absorption from mangold (Beta vulgaris): comparison of intrinsic and extrinsic labels",

abstract = "The validity of the use of extrinsic labeling for studies of manganese absorption in man was evaluated using a test meal containing Beta vulgaris intrinsically labeled with 54Mn to which 52Mn was added extrinsically. Whole body retention of the two isotopes was measured in a whole body counter during days 7-25 after administration of the test meal to six subjects. No difference in level of retention or rate of excretion was observed for the two isotopes. The calculated absorption (X = SD) was 6.0 ± 3.4% and 6.2 ± 2.9% for 54Mn and 52Mn, respectively, resulting in a 54Mn : 52Mn ratio for fractional absorption from the test meal of 0.95 ± 0.14 (X ± SD). These results demonstrate that extrinsic labeling with radioisotopes of manganese is a valid method for measurement of manganese absorption from vegetables when studied in humans.",

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author = "Lena Davidsson and Ake Cederblad and Bo L{\"o}nnerdal and Brittmarie Sandstr{\"o}m",

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AU - Davidsson, Lena

AU - Cederblad, Ake

AU - Lönnerdal, Bo

AU - Sandström, Brittmarie

PY - 1991/1/1

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AB - The validity of the use of extrinsic labeling for studies of manganese absorption in man was evaluated using a test meal containing Beta vulgaris intrinsically labeled with 54Mn to which 52Mn was added extrinsically. Whole body retention of the two isotopes was measured in a whole body counter during days 7-25 after administration of the test meal to six subjects. No difference in level of retention or rate of excretion was observed for the two isotopes. The calculated absorption (X = SD) was 6.0 ± 3.4% and 6.2 ± 2.9% for 54Mn and 52Mn, respectively, resulting in a 54Mn : 52Mn ratio for fractional absorption from the test meal of 0.95 ± 0.14 (X ± SD). These results demonstrate that extrinsic labeling with radioisotopes of manganese is a valid method for measurement of manganese absorption from vegetables when studied in humans.

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Manganese absorption from mangold (Beta vulgaris): comparison of intrinsic and extrinsic labels

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Keywords

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