Pathophysiology of prediabetes

Muhammad Abdulghani, Ralph A. DeFronzo

Research output: Contribution to journalReview articlepeer-review

86 Citations (Scopus)


The term prediabetes refers to subjects with impaired fasting glucose and/or impaired glucose tolerance who are at increased risk for type 2 diabetes mellitus. Although both types of patients are at increased risk for developing type 2 diabetes mellitus and cardiovascular disease, they manifest distinct metabolic abnormalities. In this article, we summarize the metabolic abnormalities that characterize each state and the contribution of these metabolic abnormalities to the increased risk of diabetes and cardiovascular disease.

Original languageEnglish
Pages (from-to)193-199
Number of pages7
JournalCurrent Diabetes Reports
Issue number3
Publication statusPublished - 3 Jun 2009


Dive into the research topics of 'Pathophysiology of prediabetes'. Together they form a unique fingerprint.

Cite this