Stable isotope labels as a tool to determine the iron absorption by Peruvian school children from a breakfast meal

Thomas Walczyk, Lena Davidsson, Nelly Zavaleta, Richard F. Hurrell

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Fractional iron absorption from a breakfast meal was determined in Peruvian children employing stable iron isotopes as labels. Iron isotopic analysis was performed by the recently developed negative thermal ionization technique for high-precision iron isotope ratio measurements using FeF4 - ions. By increasing the ascorbic acid content of the standard breakfast meal as served within the Peruvian school-breakfast program from 27 mg to 70 mg, it was possible to increase the geometric mean fractional iron absorption significantly from 5.1% (range 1.6-13.5%) to 8.2% (range 3.1-25.8%). Fractional iron absorption was calculated according to isotope dilution principles and by considering the non-monoisotopic character of the used spikes.

Original languageEnglish
Pages (from-to)445-449
Number of pages5
JournalFresenius' Journal of Analytical Chemistry
Volume359
Issue number4-5
DOIs
Publication statusPublished - 1 Jan 1997

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